Blood tests may replace scopes for EoE diagnosis
NCT ID NCT01988285
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study enrolled 800 adults undergoing upper endoscopy to find risk factors and blood markers that could help diagnose and monitor eosinophilic esophagitis (EoE), a chronic allergic condition of the esophagus. Researchers compared people with and without EoE, collecting blood, tissue samples, and questionnaire data. The goal is to validate a risk score and test whether blood markers like eotaxin-3 and IL-13 can reliably identify EoE and track treatment response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to simpler, less invasive ways to diagnose and monitor EoE using blood tests instead of repeated endoscopies.
What could go wrong
This is an observational study, not a treatment trial. The biomarkers may not prove accurate enough for routine use, and results may not change current care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of North Carolina, Chapel Hill
Chapel Hill, North Carolina, 27599, United States