Blood tests may replace scopes for EoE diagnosis
NCT ID NCT01988285
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study enrolled 800 adults undergoing upper endoscopy to find risk factors and blood markers that could help diagnose and monitor eosinophilic esophagitis (EoE), a chronic allergic condition of the esophagus. Researchers compared people with and without EoE, collecting blood, tissue samples, and questionnaire data. The goal is to validate a risk score and test whether blood markers like eotaxin-3 and IL-13 can reliably identify EoE and track treatment response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to simpler, less invasive ways to diagnose and monitor EoE using blood tests instead of repeated endoscopies.
- What could go wrong
- This is an observational study, not a treatment trial. The biomarkers may not prove accurate enough for routine use, and results may not change current care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of North Carolina, Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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Other studies related to the condition(s) this trial covers.
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