EOSINOPHILIC ESOPHAGITIS

This study is testing whether a diet that eliminates specific foods identified by a person's immune system tests works better than a fake diet to control Eosinophilic Esophagitis (EoE). One hundred participants, aged 16-80 with active EoE, will be randomly assigned to follow eith…

This study is testing whether children with a chronic inflammatory condition of the esophagus (Eosinophilic Esophagitis) can stay in remission using half their usual steroid dose. It aims to see if this lower dose is enough to control the disease while potentially reducing the ri…

This study is testing how well an already FDA-approved drug, dupilumab, works for people with a severe form of Eosinophilic Esophagitis (EoE) that causes dangerous narrowing of the esophagus. All 30 participants will receive weekly dupilumab injections under the skin for one year…

This study is testing whether a medication called tezepelumab, given as an injection, can help control eosinophilic esophagitis (EoE), a chronic condition that causes painful swallowing and inflammation in the food pipe. About 368 adults and adolescents with EoE will receive eith…

This study aims to check the long-term safety of an investigational drug called CC-93538 for people with eosinophilic esophagitis (EoE), a chronic inflammatory condition of the esophagus. It is open to about 368 adults and adolescents who have already taken the drug in earlier, r…

This program provided expanded access to the experimental medication APT-1011 for people with eosinophilic esophagitis (EoE) who couldn't participate in regular clinical trials or had exhausted other treatment options. Patients received a 120-day supply of the oral dissolving tab…

This study is testing a new, swallowable imaging capsule to see if it can take clear pictures of the inside of the esophagus (the food pipe). The goal is to see if this method is comfortable for people and works well enough to help doctors spot signs of a condition called Eosinop…

This study aimed to test a new, swallowable camera capsule to diagnose conditions like eosinophilic esophagitis (EoE). The goal was to see if images from the capsule were as good as those from standard, invasive biopsy procedures that require sedation. The trial was withdrawn bef…

This study aimed to understand the long-term safety of a common treatment for eosinophilic esophagitis (EoE) in children. Researchers planned to compare bone density and growth rates over one year in children aged 5-12 taking swallowed steroids for EoE against similar children no…

This study aims to understand the biological and genetic reasons why some people develop food allergies and why many children outgrow them. Researchers will collect blood samples from about 5,300 participants, including people with food allergies and healthy family members, to an…