Can half the steroid dose keep Kids' esophagitis at bay?
NCT ID NCT05309590
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looks at whether children with eosinophilic esophagitis (EoE) can safely cut their steroid dose in half and still stay in remission. The 50 participants have already achieved remission on a full dose of topical steroids like fluticasone or budesonide. Researchers will track how many maintain remission on the lower dose over time.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- topical steroids (fluticasone and budesonide)
- What this could lead to
- If successful, this could show that a lower steroid dose is enough to keep the disease under control, reducing potential side effects from long-term use.
- What could go wrong
- This is a small pilot study with only 50 children, so results may not apply to everyone. Lowering the dose might cause the disease to come back in some patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for EOSINOPHILIC ESOPHAGITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ann & Robert H Lurie Childjren's Hospital of Chicago
Chicago, Illinois, 60611, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Swallowable sponge could replace endoscopy for esophagitis monitoring
- Blood tests may replace scopes for EoE diagnosis
- Massive new registry aims to crack the code on mysterious gut disorders
- 300 kids with EoE enrolled in landmark database study
- Could ditching milk soothe a painful esophagus? new trial tests Diet-Only approach
- Can cutting four foods ease Kids' esophagus inflammation?