Can half the steroid dose keep Kids' esophagitis at bay?

NCT ID NCT05309590

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether children with eosinophilic esophagitis (EoE) can safely cut their steroid dose in half and still stay in remission. The 50 participants have already achieved remission on a full dose of topical steroids like fluticasone or budesonide. Researchers will track how many maintain remission on the lower dose over time.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
topical steroids (fluticasone and budesonide)
What this could lead to
If successful, this could show that a lower steroid dose is enough to keep the disease under control, reducing potential side effects from long-term use.
What could go wrong
This is a small pilot study with only 50 children, so results may not apply to everyone. Lowering the dose might cause the disease to come back in some patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ann & Robert H Lurie Childjren's Hospital of Chicago

    Chicago, Illinois, 60611, United States

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