Ann & Robert H Lurie Children's Hospital Of Chicago

This study is testing if a 'watch and wait' strategy for antibiotics is as safe and effective as giving them right away for children with mild pneumonia. About 2,000 children, aged 1 to 6 years, will be randomly assigned to either get antibiotics immediately or only if they don't…

This study is testing a therapy called H-HOPE to help babies born with birth defects who need surgery. It teaches parents special techniques, like gentle massage and reading baby cues, to support their infant's recovery in the hospital. Researchers want to see if this approach im…

This is a first-in-human safety study testing a new, 'off-the-shelf' cancer vaccine combined with two immunotherapy drugs for children with DIPG and DMG, aggressive brain tumors with very few treatment options. The trial aims to see if this combination is safe and tolerable for c…

This study is testing whether a smartphone app and digital sensors can help families manage children's asthma at home. Researchers want to see if adding remote support from an asthma coordinator makes the system more useful and easier to use. The trial involves 80 parent-child pa…

This study aims to help caregivers of children who visited the emergency room for suicidal thoughts or behaviors. It tests if follow-up phone calls or automated messages can better support families and reduce return visits to the ER. The goal is to find the most effective way to …

This study is testing if a medication called empagliflozin can help children with chronic kidney disease. Researchers want to see if running this type of trial is practical and if the drug improves blood, urine, and heart health markers over three months. Forty children will be r…

This study is testing if data from a Fitbit watch can help doctors detect infections earlier in children recovering from surgery for a burst appendix. Researchers will use the Fitbit's heart rate, activity, and sleep data to create an alert system for surgeons. They want to see i…

This study is testing whether a program that teaches racial justice activism can prevent depression and improve physical health in Black and Latinx teenagers and young adults. Researchers will enroll 300 participants aged 15-20 in Chicago. Half will receive activism training, whi…

This study aims to build a large database and sample collection to learn more about a group of rare digestive diseases called eosinophilic gastrointestinal disorders (EGIDs). Researchers will collect information from up to 500 patients about their symptoms, quality of life, and t…