New vaccine combo targets deadly childhood brain tumors
NCT ID NCT04943848
First seen Mar 24, 2026 · Last updated Apr 24, 2026 · Updated 1 time
Summary
This early-stage trial tests a new vaccine (rHSC-DIPGVax) combined with two immunotherapy drugs (BALSTILIMAB and ZALIFRELIMAB) in children with DIPG or DMG brain tumors. The vaccine is designed to help the immune system attack tumor cells. The study aims to find a safe dose and see if the combination can control the disease. About 36 children who have completed radiation therapy will participate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ann and Robert H. Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60611, United States
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's Health Orange County (CHOC)
RECRUITINGOrange, California, 92868, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dana-Farber Boston Children's Cancer and Blood Disorders Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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