Promising drug combo targets aggressive brain cancers in youth

NCT ID NCT07644312

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for adolescents and young adults (ages 12-39) newly diagnosed with aggressive brain tumors called high-grade glioma or DIPG. The goal is to see if a combination of two immunotherapy drugs (relatlimab and nivolumab, sold as Opdualag) is safe and tolerable when given after radiation therapy. The study will enroll 12 participants and monitor side effects and how long the cancer stays under control.

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