Ann & Robert H Lurie Children's Hospital Of Chicago

This pilot trial tests a program called TRANSIT, designed to help young adults who received heart transplants as children smoothly transition to adult care. The program includes educational modules and staff follow-up to encourage adherence to medication and care routines. Resear…

This study follows adolescents and young adults (ages 12–21) with sickle cell disease who take hydroxyurea, a medication that helps prevent pain crises and other complications. The researchers are testing whether a mobile app called HU-Go can help these patients build a consisten…

This pilot trial tests whether a smartphone app called MED-Go can help adolescents and young adults with sickle cell disease take their daily hydroxyurea more consistently. Participants aged 12 to 21 will use the app for 12 weeks, and researchers will measure how often they log t…

This study tested a program in the emergency department that uses counseling, a website, and text messages to help parents use the right car seats, booster seats, or seat belts for their children. Over 500 caregivers of children aged 6 months to 10 years took part. The goal was t…

This early-phase trial tests whether taking a daily probiotic (Saccharomyces boulardii) and using a targeted antibiotic (ciprofloxacin) only when a UTI occurs can reduce the number of repeat infections in children aged 2 to 17. Participants have had at least three UTIs in the pas…

This study tested a digital tool called iREACH that helps pediatricians follow national guidelines for introducing peanuts to infants. The tool provides reminders and education during checkups at 4, 6, 9, and 12 months. Researchers measured how well doctors followed the guideline…

This study tested a program called CEDARS that teaches teens aged 14-19 how to cope with stress and improve their mood. 36 teens took part in the online program. The goal was to see if the program was easy to use and if it helped reduce stress and improve mental health.

This study looks at whether a supraclavicular nerve block—a numbing injection placed near the collarbone during surgery—can improve pain control after elbow fracture repair in children. Researchers will compare pain scores, opioid use, and nausea rates between children who receiv…

This study tests a program called START that helps families of children with ADHD learn about the condition, reduce stigma, and overcome obstacles to getting care. About 106 children aged 6-12 with a new or recent ADHD diagnosis will take part. Some families get the START program…

This study tested whether a special nerve block given during cleft palate repair can lower pain and reduce the need for opioids in children. Forty children having their first cleft palate surgery received the nerve block. Researchers measured pain scores and opioid use to see if …

This study tested three short, one-time digital sessions (called Project YES) designed to help teens and young adults ages 13-25 who have depression, anxiety, or eating disorder symptoms. Participants completed questionnaires before the session, right after, and again 3 months la…

This study tested whether a remote monitoring bundle—including a carbon dioxide monitor, tablet, weight scale, and health app—could help doctors and families make better decisions about ventilator support for children at home. Fifty children aged 0 to 17 who use a breathing machi…

This pilot study tested a program called PRE-CARE for 54 low-income families of preschoolers with ADHD symptoms. The program helps families find and enroll in community resources like food assistance or housing support. Researchers wanted to see if this approach could reduce ADHD…

This study looks at how the antibiotic ceftazidime behaves in children with sepsis who are in the intensive care unit (ICU). Sepsis changes the body rapidly, which can affect drug levels. The goal is to see if current dosing keeps enough antibiotic in the blood to fight bacteria …

This study looks at how drug-resistant bacteria, specifically ESBL-producing E. coli, are passed from mothers to their newborns during vaginal birth or scheduled C-sections. Researchers will test stool samples from 200 healthy mothers and their babies at a Chicago hospital to see…

This study tested whether telling NICU parents to be present at least 4 hours a day (instead of 'come as you can') improves outcomes. Researchers measured stress, breastfeeding, and how long babies stayed in the hospital. 191 families took part, and the goal was to see if a simpl…

This study looked at the best ways to encourage childhood cancer survivors who are at high risk for colorectal cancer to get screened at the recommended age. Researchers tested different methods to see which helped more people complete a colonoscopy or stool-based test. The goal …