Could a diabetes drug shield Kids' kidneys? new trial launches

NCT ID NCT06430684

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial aims to see if it's possible to run a study of empagliflozin, a drug already used in adults for kidney disease, in 40 children with chronic kidney disease. Participants are randomly assigned to take the drug or continue usual care for 3 months. Researchers will check if the drug is safe and if it improves blood pressure, urine markers, and heart function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Empagliflozin (a diabetes drug that may protect kidneys and heart)

What this could lead to

If successful, this could pave the way for larger trials testing whether empagliflozin helps slow kidney disease in children.

What could go wrong

This is a very early, small feasibility study with only 40 participants and 3 months of treatment. It is not designed to prove effectiveness, and results may not apply to all children with kidney disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome kidney disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••