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Can discarded ovarian tissue reveal how childhood conditions shape future fertility?

NCT ID NCT04118712

Knowledge-focused Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This study collects discarded ovarian tissue from girls aged 0 to 18 who are having surgery on their ovary for conditions like cysts or torsion. Researchers will examine the tissue to count follicles at different stages and compare them across ages and conditions. The goal is to understand how common ovarian problems affect the number and quality of follicles and the ovary's reproductive potential.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this works, it could help doctors understand how ovarian conditions in childhood affect future fertility, and guide better ways to preserve fertility in young patients.
What could go wrong
This is an observational tissue-banking study, not a treatment trial. It may not lead directly to new therapies, and findings depend on tissue samples from a limited group of patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2016

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient recruitment could occur in either the pediatric surgery outpatient clinic or during hospital admission depending on the underlying condition and urgency of the procedure.

Ages

Up to 18 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pre and Post Pubertal females * Ages 0-18 years old * Undergoing scheduled or emergent operative procedures involving the ovary 1. oophorectomy (torsion, benign mass/cyst, malignant mass/cyst) 2. ovarian cystectomy Exclusion Criteria: * Pregnant females

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Conditions

The condition(s) this trial relates to.

malignant ovarian cyst ovarian cyst

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Benign cysts ovarian Cystectomy Malignant cysts ovarian Torsion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ann & Robert H Lurie Childrens Hospital

    RECRUITING

    Chicago, Illinois, 60611, United States

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