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Surgery's hidden toll: which ovarian cysts pose greater risk to fertility?

NCT ID NCT07686783

Knowledge-focused Sponsor: Benha University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study compares how laparoscopic removal of ovarian cysts affects ovarian reserve—a key measure of fertility potential—in women with endometriotic cysts versus non-endometriotic cysts. Researchers will measure levels of anti-Müllerian hormone (AMH) before and three months after surgery in 60 women aged 18-45 with cysts 6-15 cm in size. The goal is to understand whether the type of cyst influences the degree of ovarian function loss after surgery, which could help guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Laparoscopic ovarian cystectomy
What this could lead to
If successful, this study could help doctors predict which women are at higher risk of reduced ovarian function after cyst removal, guiding more personalized surgical decisions.
What could go wrong
This is an observational study with a small group of 60 women, so results may not apply to everyone. It measures hormone levels, not actual pregnancy or fertility outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18-45 years * Ovarian cyst measuring 6-15 cm in diameter, confirmed by transvaginal ultrasound or MRI * Cyst is persistent for more than 3 months if asymptomatic, OR any symptomatic cyst regardless of duration of diagnosis * Serum anti-Müllerian hormone (AMH) level ≥ 2 ng/mL, measured within 1 month preoperatively * Willingness to participate and provide written informed consent Exclusion Criteria: * Clinical or ultrasonic suspicion of ovarian malignancy * Ovarian cyst associated with pregnancy * Previous history of ovarian surgery * History of pelvic irradiation or chemotherapy * Known endocrine disorders affecting ovarian function (e.g., PCOS, premature ovarian insufficiency, thyroid dysfunction, hyperprolactinemia) * Current use of hormonal contraceptives or hormonal therapy within 3 months prior to enrollment * Presence of severe systemic disease that contraindicates surgery or general anesthesia * Refusal to participate or inability to provide informed consent

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Conditions

The condition(s) this trial relates to.

endometriosis ovarian cyst ovarian endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Benign ovarian cyst Cystectomy Endometriosis Ovarian cysts Ovarian reserve

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Benha Univesity Hospital

    RECRUITING

    Banhā, Qalyubia Governorate, 13512, Egypt

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