Last-Resort treatment opens for rare swallowing disorder
NCT ID NCT05095116
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This program offers APT-1011, a fluticasone tablet that dissolves in the mouth, to patients aged 12 and older with eosinophilic esophagitis who cannot join other studies or have not responded to available treatments. The goal is to provide access until the drug is commercially available. It is an open-label, single-arm program, meaning everyone gets the drug and there is no comparison group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fluticasone propionate orally disintegrating tablet
What this could lead to
If this works, it could provide a treatment option for people with eosinophilic esophagitis who have run out of other choices.
What could go wrong
This is an expanded access program, not a formal trial, so results are not designed to prove effectiveness. It is only for patients who cannot join other studies or have failed other treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Arkansas Gastroenterology
North Little Rock, Arkansas, 72117, United States
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Bernstein Clinical Research Center, LLC
Cincinnati, Ohio, 45236, United States
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Boston Specialists
Boston, Massachusetts, 02111, United States
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Bozeman Health Clinical Research
Bozeman, Montana, 59715, United States
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Carolina Research
Greenville, North Carolina, 27834, United States
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Clinical Research Institute of Michigan LLC
Chesterfield, Michigan, 48047, United States
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Clinical Research Professionals
Chesterfield, Missouri, 63005, United States
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Clinical and Translational Research Center (CTRC)
Chapel Hill, North Carolina, 27599, United States
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Del Sol Research Management LLC
Tucson, Arizona, 85715, United States
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Endoscopic Research, Inc.
Orlando, Florida, 32803, United States
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FOMAT Medical Research
Glendale, California, 91204, United States
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GI Alliance
Garland, Texas, 75044, United States
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Gastro Center of Maryland
Columbia, Maryland, 21045, United States
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Gastro Health Research
Cincinnati, Ohio, 45219, United States
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Great Lakes Gastroenterology
Mentor, Ohio, 44060, United States
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Henry Ford Health System
Novi, Michigan, 48377, United States
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MGG Group Co., Inc.
Chevy Chase, Maryland, 20815, United States
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MNGI Digestive Health, P.A.
Minneapolis, Minnesota, 55413, United States
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Medical Associates Research Group
San Diego, California, 92123, United States
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Medical Research Center of Connecticut
Hamden, Connecticut, 06518-3694, United States
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Minnesota Gastroenterology PA Plymouth Endoscopy Center Clinic
Plymouth, Minnesota, 55446, United States
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Nature Coast Clinical Research
Inverness, Florida, 34452, United States
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Northshore Gastroenterology Research LLC
Westlake, Ohio, 44145, United States
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Nuvance Health Medical Practice Ct, Inc.
Danbury, Connecticut, 06810, United States
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Peak Gastroenterology Associates
Colorado Springs, Colorado, 80907, United States
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Rapid City Medical Center LLP
Rapid City, South Dakota, 57701, United States
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Regional Gastroenterology Associates of Lancaster, Ltd.
Wyomissing, Pennsylvania, 19610, United States
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Summit Clinical Research
Athens, Georgia, 30607, United States
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United Medical Doctors
Murrieta, California, 92563, United States
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University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Ventura County Gastroenterology Medical Group Camarillo
Camarillo, California, 93012, United States
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Vital Prospects Clinical Research Institute, P.C.
Tulsa, Oklahoma, 74136, United States
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West Michigan Clinical Research Center
Wyoming, Michigan, 49519, United States
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Western States Clinical Research Inc
Wheat Ridge, Colorado, 80033, United States