EOSINOPHILIC ESOPHAGITIS

This study looked at the long-term safety of an experimental drug called CC-93538 for people with eosinophilic esophagitis, a condition where the esophagus becomes inflamed and swollen. It included 367 adults and teenagers who had already taken part in earlier studies of the same…

This study tested whether dupilumab, a drug that blocks type 2 inflammation, can help children and young adults (ages 6-25) with eosinophilic esophagitis safely add back foods like milk, egg, soy, or wheat into their diet. The 21 participants were monitored for changes in esophag…

This study tested two radioactive imaging agents (NDX-3315 and NDX-3324) in 34 adults—some healthy, some with eosinophilic esophagitis (EoE). The goal was to see if these agents can safely and accurately detect EoE inflammation using SPECT scans, potentially replacing the need fo…

This study tested a personalized diet based on immune markers in 56 people with eosinophilic esophagitis, a condition where food allergies cause throat inflammation and trouble swallowing. Participants followed either a diet that removed specific trigger foods or a sham diet. The…

This small pilot study looked at whether people with eosinophilic esophagitis (EoE) triggered by milk could tolerate baked milk in their diet. Seven participants ate baked milk for six weeks to see if their esophagus healed and symptoms improved. The goal was to find a safe amoun…

This study tested a drug called barzolvolimab in 86 adults with active eosinophilic esophagitis, a condition that causes swallowing problems due to inflammation in the esophagus. Participants received either the drug or a placebo to see if it could reduce symptoms and signs of in…

This study looked at certain immune cells in the esophagus of children with eosinophilic esophagitis (EoE), a condition that causes swallowing problems. Researchers compared these cells between 35 children with EoE and those without the condition. The goal was to learn more about…

This study looked at whether detergents found in common products like toothpaste can make the lining of the esophagus leaky and cause allergic inflammation, which is a key feature of eosinophilic esophagitis. Researchers tested 12 healthy volunteers by measuring changes in the es…