Can a drug let kids with EoE eat eggs and milk again? small trial aims to find out.
NCT ID NCT05247866
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether the drug dupilumab can help children and young adults (ages 6 to 25) with eosinophilic esophagitis (EoE) safely reintroduce foods that normally trigger their symptoms. EoE is a condition where certain foods cause inflammation in the esophagus, and current treatments often require strict food avoidance. The trial enrolled 21 participants and measured changes in esophageal inflammation and symptom scores after adding back trigger foods while on dupilumab.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dupilumab
- What this could lead to
- If successful, this could allow children with eosinophilic esophagitis to eat foods they previously had to avoid, improving their quality of life.
- What could go wrong
- This is a very small, single-site study with only 21 participants, so results may not apply to everyone. It is also a Phase 4 trial, meaning dupilumab is already approved for other conditions, but its effect on food reintroduction is still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can cutting four foods ease Kids' esophagus inflammation?