New imaging agent could spot esophagus disease without biopsy

NCT ID NCT05757856

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two radioactive imaging agents, NDX-3315 and NDX-3324, to see if they can safely and accurately detect eosinophilic esophagitis (EoE), a condition where immune cells build up in the esophagus. It involved 34 people—some healthy and some with EoE. The goal was to check safety and see if the imaging results match standard biopsy findings.

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Conditions

The condition(s) this trial relates to.

disease eosinophilic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Northwestern Univerisity

    Chicago, Illinois, 60611, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States