Blood test may guide diet to treat esophagitis

NCT ID NCT05543512

Completed Disease control Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a personalized diet, based on a blood test that identifies food allergies, can help people with eosinophilic esophagitis (EoE). 56 participants were randomly assigned to either a personalized elimination diet or a sham diet. The goal was to see if the personalized diet could reduce inflammation in the esophagus and improve swallowing symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: personalized diet based on immune signature algorithm
What this could lead to: If successful, this could lead to a more effective, personalized dietary treatment for eosinophilic esophagitis, reducing the need for trial-and-error elimination diets.
What could go wrong: This is a small pilot study, so results may not apply to everyone. The algorithm may not accurately identify trigger foods, and the diet could be difficult to follow.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EOE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

eosinophilic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EOE EOSINOPHILIC ESOPHAGITIS

Contacts and locations

Locations

The University of North Carolina at Chapel Hill

Chapel Hill, NC 27599-7080, North Carolina, 27599, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.