New drug shows promise for swallowing trouble in eosinophilic esophagitis

NCT ID NCT05774184

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 22 times

Summary

This study tested a drug called barzolvolimab in 86 adults with active eosinophilic esophagitis, a condition that causes swallowing problems due to inflammation in the esophagus. Participants received either the drug or a placebo to see if it could reduce symptoms and signs of inflammation. The goal was to find a new treatment option for people who struggle with this chronic condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advanced Research Institute - Ogden

    Ogden, Utah, 84405, United States

  • AllerVie Clinical Research

    Birmingham, Alabama, 35209, United States

  • Azienda Ospedaliera - Universitaria Integrata di Verona - Ospedale Borgo Roma

    Verona, Italy

  • Azienda Ospedaliera Universitaria OO.RR. San Giovanni di Dio Ruggi d'Aragona-Plesso "Ruggi"

    Salerno, Italy

  • Boston Specialists - Boston Food Allergy Center

    Boston, Massachusetts, 02111, United States

  • Care Access Research

    Salt Lake City, Utah, 84124, United States

  • Centrum Medyczne Med-Gastr Sp. z o.o.

    Lodz, Poland

  • Connecticut Clinical Research Institute, LLC

    Bristol, Connecticut, 06416, United States

  • Del Sol Research Management, LLC

    Tucson, Arizona, 85715, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • ENCORE Borland Groover Clinical Research

    Jacksonville, Florida, 32256, United States

  • Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore

    Rome, Italy

  • GI Alliance- Arizona Digestive Health- Sun City

    Sun City, Arizona, 85351, United States

  • GW Research Inc.

    Chula Vista, California, 91910, United States

  • Gastroenterology of Greater Orlando

    Orange City, Florida, 32763, United States

  • Hospital Clinico San Carlos

    Madrid, Spain

  • Hospital General Universitario de Alicante Dr. Balmis

    Alicante, Spain

  • IRCCS Ospedale San Raffaele

    Milan, Italy

  • Istituto Clinico Humanitas

    Rozzano, Italy

  • Klinikum Region Hannover GmbH Burgwedel

    Hanover, Germany

  • NYU Langone Health

    New York, New York, 10016, United States

  • Norfolk and Norwich University Hospital

    Norwich, United Kingdom

  • Northwestern University

    Chicago, Illinois, 60208, United States

  • One of a Kind Clinical Research Center

    Scottsdale, Arizona, 85258, United States

  • PerCuro Clinical Research Ltd.

    Victoria, British Columbia, Canada

  • Royal Adelaide Hospital

    Adelaide, South Australia, Australia

  • St George's Hospital

    London, United Kingdom

  • St Vincent's Hospital Melbourne

    Melbourne, Australia

  • St. Thomas' Hospital

    London, United Kingdom

  • Tandem Clinical Research

    Marrero, Louisiana, 70072, United States

  • The Alfred Hospital

    Melbourne, Victoria, Australia

  • The Clinical Trials Network, LLC

    Willoughby, Ohio, 44096, United States

  • The Pennsylvania State University (Penn State) Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Treasure Valley Medical Research

    Boise, Idaho, 83706, United States

  • Universitaetsklinikum Augsburg

    Augsburg, Germany

  • Universitaetsklinikum Magdeburg A.oe.R.

    Magdeburg, Germany

  • University of Calgary

    Calgary, Alberta, Canada

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Kansas Medical Center (KUMC)

    Kansas City, Kansas, 66160, United States

  • University of North Carolina (UNC) Hospitals

    Chapel Hill, North Carolina, 27514, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • Vanderbilt University Medical Center-GI Clinical Research Program

    Nashville, Tennessee, 37232, United States

  • WIP Warsaw IBD Point Profesor Kierkus

    Warsaw, Poland

  • Wojskowy Instytut Medyczny - Panstwowy Instytut Badawczy, Klinika Gastroenterologii i Chorob

    Warsaw, Poland

Conditions

Explore the condition pages connected to this study.