FDA-Approved drug shows promise for Tough-to-Treat EoE with strictures

NCT ID NCT06352073

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at how well dupilumab, an already approved drug, works for people with severe eosinophilic esophagitis (EoE) that has caused narrowing of the esophagus. About 23 participants aged 16 and older will receive weekly injections of dupilumab for one year. The goal is to see if the drug can reduce inflammation and improve swallowing, potentially reducing the need for dilation procedures.

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Conditions

The condition(s) this trial relates to.

Constriction, Pathologic eosinophilic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States