Can heating milk and egg make them safe for kids with EoE?

NCT ID NCT06381219

Recruiting now Disease control Sponsor: Universitaire Ziekenhuizen KU Leuven Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study looks at whether children with eosinophilic esophagitis (EoE) can safely eat heated forms of cow's milk and hen's egg without their disease coming back. Researchers will gradually introduce less heated versions to see if tolerance can be built. The trial involves 36 children who are currently in remission on a strict avoidance diet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: heated cow's milk and hen's egg products (baked, boiled, cooked)
What this could lead to: If successful, this could offer a way for children with EoE to safely eat some forms of milk and egg without triggering disease, improving diet and quality of life.
What could go wrong: This is a very small pilot study (36 children) with no control group, so results may not apply broadly. There is a risk that even heated allergens could cause inflammation or allergic reactions.

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Conditions

The condition(s) this trial relates to.

childhood eosinophilic esophagitis eosinophilic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EOSINOPHILIC ESOPHAGITIS

Contacts and locations

Locations

UZ Leuven Gasthuisberg
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium

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