Blood enzyme may predict knee stiffness after replacement

NCT ID NCT03598829

First seen Jan 05, 2026 · Last updated May 25, 2026 · Updated 19 times

Summary

This study looked at whether a blood enzyme called tryptase can help predict knee stiffness and pain after total knee replacement. Researchers measured tryptase levels before and after surgery in 219 people with knee arthritis. The goal was to see if changes in this enzyme are linked to a condition called arthrofibrosis, which causes stiffness after surgery.

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Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.