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5,000 knee arthritis patients tracked to crack the treatment code

NCT ID NCT03746184

Knowledge-focused Sponsor: Hvidovre University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Knee osteoarthritis treatments vary widely, and doctors lack clear guidance on which option suits which patient. This study follows 5,000 people with knee osteoarthritis who receive usual care, recording the treatments they get and how they fare. Researchers aim to map common treatment paths, find patient factors that predict a good outcome, and measure the economic burden of different approaches.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the study identifies which patient factors predict a good response, doctors could match people with knee osteoarthritis to the treatments most likely to help them.
What could go wrong
This is an observational study, so it can show patterns but cannot prove that a treatment causes a better outcome. Results may not apply outside the Danish clinics where researchers collect the data.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

3,507 people

The number who actually took part.

Started

Oct 2018

Finished

Apr 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients with primary referrals to one of two public hospitals orthopedic department's outpatient clinics due to knee osteoarthritis are consecutively invited to participate. The two hospitals cover the larger part of Zealand in Denmark.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * primary referrals to one of two orthopedic department's outpatient clinics due to knee osteoarthritis Exclusion Criteria: * previous total or unicompartmental knee replacement * osteotomy around the study knee * unable to read or write Danish * patients who decline to answer the questionnaire at inclusion

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • Department of Orthopaedic Surgery, Copenhagen University Hospital Hvidovre

    Hvidovre, 2650, Denmark

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