New hope for tough breast cancer: drug combo shows promise in trial

NCT ID NCT02860000

First seen Jan 10, 2026 · Last updated May 14, 2026 · Updated 16 times

Summary

This study tested a drug called alisertib, either alone or with another drug called fulvestrant, in 96 postmenopausal women with advanced breast cancer that had stopped responding to hormone therapy. The goal was to see if these treatments could shrink tumors. While the approach aims to control the disease, it is not a cure, and ongoing management is expected.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Georgetown University Medical Center

    Washington D.C., District of Columbia, 20007, United States

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • Vanderbilt Breast Center at One Hundred Oaks

    Nashville, Tennessee, 37204, United States

Conditions

Explore the condition pages connected to this study.