CBD cream shows promise for chemo nerve pain in small trial

NCT ID NCT05388058

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a topical cannabidiol (CBD) cream against a placebo cream to see if it could reduce nerve pain, numbness, and tingling in the hands and feet caused by chemotherapy. Forty adults with moderate to severe chemotherapy-induced peripheral neuropathy (CIPN) applied the cream daily for four weeks. The goal was to find a well-tolerated option for a condition that is often hard to treat with standard medications.

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Conditions

The condition(s) this trial relates to.

cancer chemotherapy-induced neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fairview Grand Itasca Clinic and Hospital

    Grand Rapids, Minnesota, 55744, United States

  • Fairview Northland Medical Center

    Princeton, Minnesota, 55371, United States

  • Fairview Range Medical Center

    Hibbing, Minnesota, 55746, United States

  • Mayo Clinic Health System Albert Lea

    Albert Lea, Minnesota, 56007, United States

  • Mayo Clinic Health System Mankato

    Mankato, Minnesota, 56001, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

  • Monticello Cancer Center

    Monticello, Minnesota, 55362, United States

  • Sanford Thief River Falls

    Thief River Falls, Minnesota, 56701, United States

  • Sanford Worthington

    Worthington, Minnesota, 56187, United States