Heart imaging may reveal hidden clues in rare heart disease

NCT ID NCT05379101

Completed Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study uses advanced heart imaging to understand how blood flows inside the heart in people with cardiac amyloidosis, a condition where abnormal proteins build up in heart tissue. Researchers will compare these images with those from healthy volunteers to find unique patterns, or biomarkers, that could help diagnose or track the disease. Participants will undergo MRI scans, echocardiograms, and a six-minute walk test.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could identify new imaging markers to help diagnose or monitor cardiac amyloidosis more accurately.
What could go wrong: This is an observational study, not a treatment trial. It may not lead to direct patient benefits or change clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

AL amyloidosis Amyloid Neuropathies, Familial wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYLOIDOSIS CARDIAC HEALTHY ADULTS

Contacts and locations

Locations

Mayo Clinic

Rochester, Minnesota, 55905, United States

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