AMYLOIDOSIS CARDIAC

This study looks at heart tissue samples from 216 adults who already need a biopsy as part of their care. Researchers want to find unique molecular patterns for different heart conditions, like cardiomyopathy and heart transplant recovery. The goal is to improve how doctors diagn…

This study follows 200 adults with a heart condition called ATTR amyloidosis who are taking the drug tafamidis. Researchers will check for dangerous heart rhythm problems every six months using standard tests like electrocardiograms and Holter monitors. The goal is to better unde…

This study is for people with cardiac amyloidosis who are starting a new medication. It uses advanced heart scans (ultrasound, MRI, and PET) to look at changes in the heart muscle over one year. The goal is to learn why the disease continues to get worse in about one-third of pat…

This study looks at whether tiny particles released by cells into the blood, called extracellular vesicles, can help detect heart damage from ATTR amyloidosis earlier and less invasively. Researchers will compare these particles in 70 people with different stages of the disease a…

This study is creating a biobank and data registry for people with amyloidosis, a rare disease where abnormal proteins build up in organs. Researchers will collect blood, urine, and tissue samples along with medical information from 505 participants. The goal is to store these ma…

This study is testing whether a special ultrasound treatment can improve blood flow and heart function in people with cardiac amyloidosis, a condition where abnormal proteins build up in the heart. Researchers will compare results from 70 participants, including those with the di…