Heart rhythm risks in ATTR amyloidosis patients on tafamidis under scrutiny
NCT ID NCT06251778
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 200 adults with ATTRwt amyloidosis who are taking tafamidis to see how often they develop heart rhythm problems that need a pacemaker or defibrillator. Researchers will also track changes in diuretic use. Participants are checked every six months as part of routine care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tafamidis
What this could lead to
If successful, this study could improve how doctors monitor and manage heart rhythm problems in people with ATTR amyloidosis.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to new therapies, and results depend on routine care, which varies.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Fondazione IRCCS Policlinico San Matteo
RECRUITINGPavia, 27100, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••