Heart rhythm risks in ATTR amyloidosis patients on tafamidis under scrutiny

NCT ID NCT06251778

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 200 adults with ATTRwt amyloidosis who are taking tafamidis to see how often they develop heart rhythm problems that need a pacemaker or defibrillator. Researchers will also track changes in diuretic use. Participants are checked every six months as part of routine care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tafamidis
What this could lead to
If successful, this study could improve how doctors monitor and manage heart rhythm problems in people with ATTR amyloidosis.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to new therapies, and results depend on routine care, which varies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies, Familial amyloidosis wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fondazione IRCCS Policlinico San Matteo

    RECRUITING

    Pavia, 27100, Italy

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