Blood particles may reveal hidden heart disease
NCT ID NCT07314268
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether tiny particles released by cells into the blood, called extracellular vesicles, can help detect a type of heart disease called ATTR amyloidosis earlier. The disease often goes unnoticed until serious damage occurs. Researchers will compare these particles in 70 people with and without the condition, using blood tests and heart imaging, to see if they can serve as early warning signs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple blood test for earlier detection of ATTR amyloid cardiomyopathy, potentially improving treatment timing and outcomes.
What could go wrong
This is an early observational study with only 70 participants. The findings may not translate into a reliable clinical test, and the biomarkers may not prove useful for diagnosis or prognosis.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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Instituto do Coracao, HCFMUSP
RECRUITINGSão Paulo, São Paulo, 05403000, Brazil
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