AMYLOIDOSIS, HEREDITARY
Clinical trials for AMYLOIDOSIS, HEREDITARY explained in plain language.
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Gene-Editing shot aims to halt rare nerve disease in phase 3 trial
Disease control Recruiting nowThis phase 3 trial tests a single dose of NTLA-2001, a gene-editing therapy, in 60 adults with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN), a rare genetic disease that damages nerves. Participants are randomly assigned to receive either the active treatmen…
Matched conditions: AMYLOIDOSIS, HEREDITARY
Phase: PHASE3 • Sponsor: Intellia Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Hidden heart risk: study aims to catch deadly protein buildup before symptoms start
Knowledge-focused Recruiting nowThis study is looking for early signs of heart amyloidosis in Black adults who carry a specific gene change (V122I TTR) that raises their risk. Researchers will use heart MRI scans and blood tests to detect protein buildup before symptoms appear. The goal is to find ways to diagn…
Matched conditions: AMYLOIDOSIS, HEREDITARY
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Blood particles may reveal hidden heart disease
Knowledge-focused Recruiting nowThis study looks at whether tiny particles released by cells into the blood, called extracellular vesicles, can help detect a type of heart disease called ATTR amyloidosis earlier. The disease often goes unnoticed until serious damage occurs. Researchers will compare these partic…
Matched conditions: AMYLOIDOSIS, HEREDITARY
Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC