HEALTHY ADULTS

This study is testing new mRNA-based flu vaccines to see how safe they are and how well they trigger the body's immune response. It involves about 770 healthy adults who will receive one shot and be followed for about 6 months. The new vaccines are being compared to currently app…

This is an early safety study testing a new gene therapy injection in healthy adults aged 50-80. The therapy aims to deliver two genes, klotho and follistatin, which may improve physical function, thinking skills, and overall health. Researchers will monitor participants closely …

This study compares two ways to place dental implants to see which is more accurate. One method uses a custom-made plastic guide, while the other uses a computer screen to guide the dentist in real-time. Researchers will measure how precisely the implants are placed, how long eac…

This study is testing whether taking a daily probiotic supplement can help prevent common travel-related health problems. Healthy adults taking short trips abroad will take either the probiotic or a placebo pill to see if it stabilizes their gut health, reduces diarrhea and stoma…

This study compares two different therapy combinations to help people recover leg movement after a stroke. Researchers will test mirror therapy paired with either gentle electrical muscle stimulation or special sound patterns called binaural beats. The goal is to see which approa…

This study is testing whether two simple, non-drug approaches can help people exercise more easily in low-oxygen conditions, like at high altitude. Healthy, active adults will try either breathing muscle training, drinking beetroot juice (a natural nitrate source), both, or neith…

This is an early, first-in-human study to check the safety and see how the body handles a new drug called EDG-15400. Healthy adult volunteers will take either the drug or a placebo by mouth. The main goal is to learn about side effects and how the drug moves through the body in d…

This study aims to learn if eating pecans daily improves overall health in middle-aged and older adults. For about 7 months, 40 healthy participants will alternate between eating pecans and avoiding them. Researchers will measure changes in heart health, gut bacteria, blood marke…

This study aims to find better, more objective ways to measure what people eat by looking for chemical clues in blood and urine. Researchers will feed 30 healthy adults two different diet patterns—one healthier and one less healthy—in a controlled setting. They will analyze sampl…

This study aims to understand how a common drug, carbamazepine, changes how the body processes an experimental Pfizer drug called PF-07248144. It involves 12 healthy adults who will take PF-07248144 alone and then with carbamazepine. Researchers will take blood samples to measure…

This is an early safety study to see how healthy adults tolerate a new drug called GS3-007a. Researchers will give different doses to small groups of volunteers to check for side effects and measure how the drug moves through the body. The goal is to gather basic safety informati…

This study aims to understand how much our genes versus our diet affect our weight and metabolism. Researchers in Pakistan will have 60 pairs of identical and non-identical twins follow a balanced diet for 12 weeks. By comparing the twins' responses, they hope to learn how to giv…

This is a first-step safety study testing a new gene therapy injection designed to increase levels of a protein called Klotho in healthy adults. Researchers will give 24 volunteers a single injection and then closely monitor them for any side effects. They will also run many bloo…

This study aims to find out if using infrared heat or a therapeutic massage is better as a warm-up before exercise. Researchers will measure how these methods affect jump height, balance, and flexibility in 100 healthy young adults. The goal is to gather knowledge to help people …

This is a first-in-human study to check the safety and side effects of a new oral drug called MIB-725. It will be given in single, increasing doses to 32 healthy adults to see how their bodies react and process it. The main goal is to find a safe dose range for future studies tha…

This study aims to understand how two existing medications (itraconazole and probenecid) affect how the body processes a single dose of a new, experimental drug called PF-07220060. It involves 28 healthy adult volunteers who will take the new drug alone and then again while takin…