HEALTHY ADULTS

This study tested a home-use device that uses two types of light to kill bacteria on teeth. 20 healthy adults used the light treatment along with brushing and flossing, and researchers measured how much plaque remained. The goal was to see if the light device could clean areas th…

This study looked at how an inhaled drug called treprostinil affects exercise ability in people with pulmonary hypertension caused by interstitial lung disease. 29 participants took the drug for 3 months. Researchers measured heart function and breathing efficiency during exercis…

This study tested whether a chicken extract supplement can improve mental energy—like focus, motivation, and tiredness—in 189 healthy adults aged 35-64. Participants took the supplement or a placebo for a period, and researchers measured reaction time, attention, and brain activi…

This study tested whether omega-3 supplements (a healthy fat found in fish oil) can reduce stress, anxiety, and depression, and improve memory and sleep. 64 Saudi adults with high stress took either omega-3 or a placebo daily for three months. Results showed that those taking ome…

This study looked at how two common drugs—cyclosporine (an immune suppressant) and clarithromycin (an antibiotic)—change the way the body processes a new medicine called PF-07328948. 26 healthy adults took part. The goal was to gather safety and drug-level information, not to tre…

This study looked for chemicals in blood and urine that can show what foods a person has eaten, like beef, beans, or eggs. Thirty healthy adults ate controlled meals and gave samples over several days. The goal was to find more accurate ways to measure diet than asking people to …

This study followed over 5,000 adults aged 55-70 for eight years to learn about retirement, loneliness, and physical activity. Researchers interviewed participants three times between 2013 and 2019. The goal was to understand how people transition into old age, not to test any tr…

This study tested how bismuth subsalicylate (the active ingredient in Pepto-Bismol) affects the bacteria living in the gut. 34 healthy adults took the medicine for 2 days, and researchers compared their stool samples before and after. The goal was to understand how this common st…

This study looked at how four different versions of a supplement called Urolithin A (Mitopure) are absorbed by the body. 48 healthy adults aged 18 to 45 took a single dose of one version. Researchers measured levels of the supplement in the blood over time to see which form works…

This early-stage study tested whether a new substance called CHI-554 is safe when taken with alcohol. 29 healthy adults took part in a double-blind, randomized trial. The main goal was to check for side effects and changes in blood pressure and liver function. This study does not…

This study looks at how the drug carbamazepine changes the way the body handles another drug, PF-07248144. It involves 12 healthy adults who will take PF-07248144 alone and then with carbamazepine. Researchers will measure drug levels in the blood to understand the interaction an…

This study looked for natural markers in blood and urine that show what people have eaten, instead of relying on memory or food diaries. Thirty-two healthy adults ate carefully controlled meals, and researchers measured how their bodies processed different foods. The goal is to c…

This study looked at how two other drugs (itraconazole and probenecid) change the way a new medicine (PF-07220060) works in the body. It involved 25 healthy adults who took the new medicine alone and then with the other drugs. The goal was to understand any interactions to help d…

This study looked at how healthy men process the experimental drug PF-07104091. Nine participants took the drug by mouth and later received a tiny radioactive version by IV. Researchers measured how much of the drug entered the blood and how it was removed in urine and stool. The…

This study looks at how the drug carbamazepine changes the way the body handles a new medicine called PF-07220060. It involves 14 healthy adults aged 18 to 65. Participants take PF-07220060 once alone and once after several days of carbamazepine, with blood samples collected to m…

This study looked at whether a special video game that combines physical exercise with mental challenges can improve attention and working memory in healthy adults. 49 participants were assigned to different training groups for 8 weeks. The goal was to understand if combining phy…

This study looked at how the liver's health affects the way a drug called KP-001 moves through the body and its safety. It included 24 adults, some with liver problems and some healthy. Participants received a single dose of KP-001, and researchers measured drug levels in the blo…

This completed Phase 1 study by Pfizer involved 24 healthy adults to compare how the body absorbs two different pill forms of an experimental drug called PF-07248144. Participants received a single dose of each form in a crossover design, and researchers measured drug levels in t…

This study looked at how one session of aerobic exercise at different intensities affects brain blood flow, stress markers, and memory in healthy adults and those with mild stress. 24 people aged 20-40 participated. The goal was to understand the immediate benefits of exercise on…