Pfizer tests drug interactions in healthy volunteers

NCT ID NCT06837259

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 study looked at how two common drugs—cyclosporine and clarithromycin—affect the levels of a new experimental medicine called PF-07328948 in the body. Twenty-six healthy adults received PF-07328948 alone and then with cyclosporine or clarithromycin. The goal was to understand drug interactions and safety, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PF-07328948
What this could lead to
If successful, this study could help determine safe and effective dosing of PF-07328948 when taken with other drugs.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. Results may not predict real-world effects or safety.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pfizer Clinical Research Unit - Brussels

    Brussels, Bruxelles-capitale, Région de, B-1070, Belgium

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