HEALTHY ADULTS

This study tests if gentle electrical stimulation to leg muscles can help children with cerebral palsy walk more easily. About 65 children (ages 7-18) will walk on a treadmill while different stimulation settings are compared. The goal is to find which method works best to improv…

This study tests whether combining repetitive transcranial magnetic stimulation (rTMS) with expressive writing can reduce post-traumatic stress symptoms in adults. Forty-five participants who have experienced a traumatic event will be split into three groups: rTMS before writing,…

This study tests a supplement called Origin Satiety Complex to see if it helps healthy adults feel less hungry and more full after eating. About 30 people will take either the supplement or a placebo and rate their hunger and fullness over 10.5 hours. The goal is to find a safe w…

This study investigates how the experimental cancer drug atirmociclib is processed by the body in people with mild, moderate, or severe liver disease compared to those with healthy livers. Participants receive a single oral dose of the drug, and blood samples are taken over time …

This study aims to see if magnetic resonance spectroscopy (MRS) can accurately measure NAD+ levels in the brain and calf muscles of healthy adults. Participants will take an over-the-counter nicotinamide riboside (NR) supplement, and researchers will compare NAD+ measurements bef…

This study looks at whether a special high-resolution MRI can show very small nerves in the neck and spine better than a regular MRI. Researchers will scan 30 healthy adults for 30 minutes and check how clearly the nerves appear. The goal is to find a way to see nerve injuries th…

This study tests whether taking statins (a common cholesterol drug) can protect the heart and brain from the harmful effects of breathing bushfire smoke. Healthy adults aged 18-64 will be exposed to simulated smoke in a controlled setting, with some taking statins short-term (2 d…

This study looks at how different amounts of oral THC (the main psychoactive ingredient in cannabis) affect mood, heart rate, and drug feelings in healthy adults who have used cannabis before. Participants will take either a low, medium, or high dose of THC or a placebo during fo…

This study will measure a specific heart function index in 2,640 healthy adults and people with heart conditions using AI-enhanced 3D ultrasound. The goal is to establish normal ranges and see how this measurement changes in diseases like heart failure and high blood pressure in …