Liver health may change how a promising cancer drug works in the body
NCT ID NCT07677358
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study investigates how the experimental cancer drug atirmociclib is processed by the body in people with mild, moderate, or severe liver disease compared to those with healthy livers. Participants receive a single oral dose of the drug, and blood samples are taken over time to measure drug levels. The goal is to see if liver impairment alters how the drug behaves, which could guide safer dosing for patients with liver issues. The study involves about 28 adults and lasts roughly 9 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- atirmociclib
- What this could lead to
- If successful, this study could help doctors determine the right dose of atirmociclib for patients with liver problems, making the drug safer to use.
- What could go wrong
- This is an early-phase study with only 28 participants, so results may not apply to everyone. The drug may still cause side effects regardless of liver function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Floridian Clinical Research
Miami Lakes, Florida, 33016, United States
-
Genesis Clinical Research
Tampa, Florida, 33603, United States
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Orlando Clinical Research Center
Orlando, Florida, 32809, United States
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