Can an MRI spot your Body's 'Anti-Aging' molecule?

NCT ID NCT07416786

Not yet recruiting Knowledge-focused Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to see if magnetic resonance spectroscopy (MRS) can accurately measure NAD+ levels in the brain and calf muscles of healthy adults. Participants will take an over-the-counter nicotinamide riboside (NR) supplement, and researchers will compare NAD+ measurements before and after supplementation. The goal is to standardize NAD+ measurement methods for future clinical studies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nicotinamide Riboside (NR) supplement
What this could lead to: If successful, this could help develop a reliable way to measure NAD+ in humans, which may aid future research on aging and metabolism.
What could go wrong: This is a small, early-stage study focused on measurement methods, not treatment. It may not lead to any direct health benefits.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY ADULTS

Contacts and locations

Locations

Penn Medicine

Philadelphia, Pennsylvania, 19104-6006, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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