Pfizer tests drug interaction in 12 healthy volunteers

NCT ID NCT07636018

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 study tested how the antifungal drug fluconazole changes the way the body processes an experimental drug called PF-07248144. Twelve healthy adults took PF-07248144 alone and then again with fluconazole. Researchers measured drug levels in the blood to understand the interaction and check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PF-07248144 and fluconazole
What this could lead to
If successful, this study could help determine the right dose of PF-07248144 when taken with fluconazole, improving safety and effectiveness in future trials.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. It only looks at drug levels and safety, not whether PF-07248144 works for any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pfizer Clinical Research Unit - Brussels

    Brussels, Bruxelles-capitale, Région de, B-1070, Belgium

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