Can a pill mop up hidden leukemia cells after chemo?

NCT ID NCT02649387

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug ibrutinib in 35 people with chronic lymphocytic leukemia (CLL) who still had small amounts of cancer cells after their first treatment. The goal was to see if ibrutinib could clear those leftover cells from the blood and bone marrow. Participants took ibrutinib pills, and doctors checked for minimal residual disease (MRD) over time. The approach aims to control the disease long-term, not cure it, since ongoing treatment is needed.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

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