New combo shows promise for tough lymphomas
NCT ID NCT02213913
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested adding lenalidomide to a standard chemotherapy regimen (EPOCH-R) in 55 people with aggressive B-cell lymphomas linked to the MYC gene. The goal was to find the best dose and see if the combination improves how long patients live without their cancer getting worse. The trial is complete, and results help guide future treatment options.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lenalidomide
What this could lead to
If successful, this combination could offer a more effective treatment option for aggressive B-cell lymphomas with MYC gene changes.
What could go wrong
This is an early-phase trial with only 55 participants, so results may not apply to all patients. Side effects from the chemotherapy combination can be severe.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Decatur Memorial Hospital Cancer Care Institute
Decatur, Illinois, 62526, United States
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Illinois Cancer Care
Peoria, Illinois, 61615, United States
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NorthShore University HealthSystem
Evanston, Illinois, 60201, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Maryland
Baltimore, Maryland, 21202, United States