Can 3D-Printed models unlock personalized blood cancer therapies?

NCT ID NCT07759661

First seen Aug 12, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study aims to create 3D models of B-cell cancers—like chronic lymphocytic leukemia, splenic marginal-zone lymphoma, and hairy cell leukemia—using blood samples from patients. The goal is to build realistic models that mimic the tumor environment, which could help researchers test and personalize treatments. Adults with these conditions who are receiving standard care may participate by donating extra blood during routine draws.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Patient-derived 3D bioprinted models
What this could lead to
If successful, this could lead to more personalized and effective treatments for B-cell cancers like CLL, SMZL, and HCL.
What could go wrong
This is an early-stage laboratory study, so the models may not perfectly mimic real patient responses, and results may not directly translate to new treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Ospedale San Raffaele

    Milan, MI, 20132, Italy

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