Leukemia drug study probes thinking and memory side effects

NCT ID NCT07638007

First seen Jun 11, 2026 · Last updated Jun 22, 2026 · Updated 4 times

Summary

This study looks at whether targeted cancer drugs called TKIs affect brain health and well-being in people with chronic leukemia. Researchers will compare 400 patients who receive TKI therapy to those who do not. The goal is to understand if these treatments cause cognitive changes, helping guide future care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Rochester NCORP Research Base

    RECRUITING

    Rochester, New York, 14642, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tyrosine kinase inhibitor (TKI) therapy

What this could lead to

If successful, this could help doctors understand whether TKIs affect brain function and quality of life in leukemia patients.

What could go wrong

This is an observational study, not a treatment trial. It may not find clear differences, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia chronic myelogenous leukemia, BCR-ABL1 positive disease Leukemia, Myelogenous, Chronic, BCR-ABL Positive

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.