Two devices may be better than one for obesity treatment
NCT ID NCT05559866
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether combining two endoscopic procedures—Hybrid Argon Plasma Coagulation (HAPC) and Endoscopic Sleeve Gastroplasty (ESG)—is safer and more effective than ESG alone for weight loss. The trial included 45 adults with obesity (BMI 30–40) who had not succeeded with non-surgical methods. The main goal was to see if the combination made the sutures last longer at 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hybrid Argon Plasma Coagulation (HAPC) and Endoscopic Sleeve Gastroplasty (ESG) devices
What this could lead to
If successful, this combination could make endoscopic weight-loss procedures more durable and effective for people with obesity.
What could go wrong
This is a small, single-center trial with only 45 participants. The primary outcome is about suture durability, not long-term weight loss, so results may not translate to lasting benefits.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mayo Clinic Rochester
Rochester, Minnesota, 55905, United States