Pregnancy disorder

This study tested a program that combines community-based fetal ultrasound with care navigation to help pregnant women with substance use disorder engage in prenatal care and substance use treatment. The program used motivational interviewing and strength-based education to suppo…

This pilot trial tests whether a social media platform can provide continuous dietary and lifestyle support for women with gestational diabetes. Forty pregnant women diagnosed with gestational diabetes receive either usual care from a diabetes nurse and dietitian, or usual care p…

Pre-eclampsia is a serious pregnancy complication that can harm both mother and baby, and the only cure is delivering the baby. Researchers are testing whether citrulline, a natural amino acid, can safely prolong pregnancy for women hospitalized with pre-eclampsia before 36 weeks…

This study tests whether giving doctors a reminder and providing patients with a one-page handout can help women who had gestational diabetes or high blood pressure during pregnancy get a primary care visit within six months of delivery. The goal is to prevent future diabetes and…

This study tests whether giving probiotics to pregnant women with diabetes can improve their babies' brain development. Researchers will give 60 mothers a probiotic supplement and then measure their infants' brain responses to sounds and sights at 1 and 6 months old. The goal is …

This trial tests three medications, phenylephrine, norepinephrine, and ephedrine, to see which one best manages low blood pressure that can occur after spinal anesthesia in women with preeclampsia having a cesarean delivery. Researchers will give each participant one of the three…

This study tested two lifestyle programs for overweight or obese pregnant women to help them manage weight gain during pregnancy. One group received weekly group sessions on diet and activity, while the other got extra health information and classes. Researchers tracked weight ga…

This study tests whether hydroxytyrosol, a natural antioxidant from olives, can improve blood vessel function in pregnant women with high blood pressure. Fifty-two women will take either the supplement or a placebo for 4 weeks. Researchers will measure changes in blood markers an…

This trial compares two methods of amnioinfusion—adding fluid to the womb—in pregnant women with preterm premature rupture of membranes (PPROM) and very low amniotic fluid. One method uses a central venous pressure (CVP) set for controlled fluid delivery, while the other uses the…

This trial tests whether a 10-week therapeutic exercise program, including relaxation and stretching, can influence the mode of delivery in first-time mothers aged 35-40 who have a rigid perineum. Participants are randomly assigned to either the exercise program plus routine advi…

This study looks at whether allowing a slightly higher blood sugar range (70-110 mg/dL) during labor in mothers with diabetes can reduce the number of newborns with low blood sugar. Researchers will compare this approach to standard care in 169 pregnant women planning a vaginal d…

This trial compares two surgical strategies for managing placenta accreta, a condition where the placenta grows too deeply into the uterine wall and can cause severe bleeding during delivery. One approach is a caesarean hysterectomy, which removes the uterus after the baby is bor…

This study tested whether community health workers can help Black postpartum patients who had preeclampsia or other pregnancy complications. 61 participants were split into two groups: one received usual care, the other also got support from a community health worker. The goal wa…

This trial tests whether a soft balloon (Cook's balloon) placed in the cervix is better than a vaginal medication (dinoprostone) for starting labor in full-term pregnancies where the baby is growing slowly. The main goal is to see which method leads to more vaginal deliveries and…

This study tests whether a wireless monitor worn for 24 hours after an emergency C-section can alert doctors when a new mother's vital signs become dangerous. Over 3,000 women in Uganda will wear the device, which sends alerts if heart rate, blood pressure, or other readings fall…

This study tests whether extremely low birth weight infants (born before 29 weeks) who receive donor human milk during their hospital stay have better brain development than those given preterm formula. Infants whose mothers cannot or choose not to breastfeed are randomly assigne…

This study tests whether a more intensive approach—combining a structured low-calorie diet, moderate exercise, and frequent monitoring—works better than standard counseling for managing gestational diabetes. Sixty pregnant women will be randomly assigned to one of two groups. The…

This study tests whether intensive dietary counseling from a dietitian can help women with gestational diabetes control blood sugar without needing insulin. 214 women will be randomly assigned to either intensive nutrition support or standard care. The main goal is to see if more…

This study tested whether giving pregnant women a balanced energy and protein supplement (BEP) can improve birth weight and reduce complications like low birth weight and preterm birth. Over 3,300 women in Bangladesh were randomly assigned to receive either BEP or standard prenat…

This study investigates whether a structured, personalized exercise plan—tracked with a smartwatch and supported by regular phone check-ins—can help control blood sugar, blood pressure, and weight gain in pregnant women with gestational diabetes, chronic hypertension, or obesity.…

This trial tests whether repeatedly adding sterile fluid into the womb can help fetuses with severe kidney failure grow enough lungs to survive after birth. Pregnant women with early pregnancy kidney failure can choose to receive the infusions or just be monitored. Babies who sur…

This study tests whether using continuous positive airway pressure (CPAP) or positive end-expiratory pressure (PEEP) during resuscitation helps extremely low birth weight infants (born before 28 weeks) breathe better and avoid lung damage. Half of the babies receive standard care…

This study tests whether a single intravenous dose of ferumoxytol raises hemoglobin more effectively than daily oral ferrous sulfate in pregnant women with iron deficiency anemia. Participants are between 24 and 34 weeks pregnant with a single baby. The trial measures hemoglobin …

This pilot study tested whether waiting 30-45 seconds before clamping the umbilical cord, instead of clamping immediately, is feasible and might improve blood health in extremely low birth weight premature infants (24-27 weeks gestation). 54 infants were enrolled. The goal was to…

This study tested whether adding a smartphone app with short videos on mental health, diet, exercise, and insulin adjustment to standard care could improve blood sugar control and birth weight in pregnant women with diabetes. Over 600 women participated. The goal was to see if th…

This study tested whether adding letrozole to misoprostol helps end a nonviable pregnancy in the first trimester more effectively than misoprostol alone. 400 women with missed miscarriage took part. Researchers measured bleeding, time to complete abortion, and side effects.

This study tested whether a once-monthly injection of buprenorphine works as well as daily pills to treat opioid use disorder in 140 pregnant women. The goal was to see if the monthly shot could reduce illicit opioid use during pregnancy and after birth. Results help doctors choo…

This study tested whether a stricter blood pressure goal (below 135/85) after a pregnancy complicated by high blood pressure is better than the usual care (below 150/100). About 60 new mothers were enrolled and followed for six months. The goal is to see if tighter control is pos…

This study tested a smartphone app designed to help women with gestational diabetes manage their condition during pregnancy. The app was developed with input from patients in Nepal and aimed to support self-care like tracking blood sugar and lifestyle habits. Researchers enrolled…

This study compared insulin injections and metformin pills in 60 pregnant women with gestational diabetes to see which is safer and more effective. Participants were randomly assigned to receive either insulin or metformin, and researchers monitored blood sugar levels and newborn…

This study tested whether filling the bladder with a blue dye before surgery helps surgeons avoid accidentally injuring the bladder or ureters during a cesarean hysterectomy for placenta accreta. Sixty women were randomly assigned to receive the dye or standard care. The goal was…

This study looked at how the diabetes drugs glyburide and metformin work in pregnant women with gestational diabetes. 177 women between 20 and 32 weeks pregnant took part. The goal was to find the right dose and understand how these drugs control blood sugar and improve insulin f…

This completed study compared two intravenous blood pressure medications, labetalol and hydralazine, in 132 pregnant women with severe preeclampsia. The goal was to see which drug more effectively lowered blood pressure to safe levels. Results could help doctors in the local sett…

This study tested two different blood pressure targets during cesarean section in 390 women with preeclampsia. One group kept blood pressure above 80% of their starting level, the other above 90%. The goal was to see which target led to better newborn outcomes, measured by umbili…

This study tested a counseling program for couples in Zambia to help pregnant women living with HIV stay healthy. Nearly 500 couples took part. The program aimed to improve HIV medication adherence and viral suppression through relationship strengthening.

This study tested two doses of tranexamic acid (a drug that helps blood clot) to see if it could reduce blood loss during cesarean deliveries when heavy bleeding occurs. 225 women who experienced significant bleeding during a planned or non-emergency C-section were randomly given…

This study tested whether sodium bicarbonate (a common substance) can safely treat acidosis—a dangerous buildup of acid in the blood—in women whose labor is blocked. About 472 women in Uganda received either the drug or a placebo. The goal was to find a safe, effective dose to im…

This study looked at whether a fast blood test (ROTEM) done during surgery for placenta accreta can help doctors decide when to give blood transfusions. 32 women took part, with half getting the rapid test and half getting standard lab tests. The goal was to see if the rapid test…

This early-stage trial tested the safety and tolerability of telpegfilgrastim injections in 18 non-pregnant women, including some with a history of preeclampsia. Researchers monitored side effects, drug levels in the blood, and immune markers. The goal is to see if the drug is sa…

This study tested a mobile health lifestyle program for 200 overweight or obese pregnant women in China. Participants used a WeChat account and a Huawei wristband to track diet, exercise, and weight, and received personalized feedback. The goal was to see if this approach could h…

This study tested whether using a continuous glucose monitor (CGM) in the hospital right after childbirth could better detect low blood sugar (hypoglycemia) in women with type 1 or type 2 diabetes, compared to standard finger-stick tests. Thirty-nine women in their third trimeste…

This study looked at two different ways to manage blood sugar in pregnant women with MODY2 diabetes, a genetic condition that affects insulin release. The goal was to see if using ultrasound to guide insulin treatment could prevent the baby from growing too large. 46 women took p…

This early-stage study tested whether a brief therapy program plus a mobile app could help pregnant and postpartum women stay on their buprenorphine medication for opioid use disorder. Fifteen pregnant women took part, attending therapy sessions and using the app for up to 9 mont…

This study tested whether taking low-dose aspirin (150 mg) daily, starting in the first trimester, could reduce pregnancy complications in women with type 1 or type 2 diabetes. The trial included 137 women and looked at outcomes like preeclampsia, early preterm birth, low birth w…

This study tested a nutrition checklist and educational module (M-FIGO) designed for Malaysian women with gestational diabetes. 206 pregnant women were randomly assigned to receive either the checklist plus standard care or standard care alone. The goal was to see if the tool hel…

This completed trial tested whether taking vitamin D and calcium supplements for six weeks could improve blood sugar and cholesterol levels in 60 pregnant women diagnosed with gestational diabetes. The study measured fasting blood sugar, HbA1c, and lipid profiles to see if the su…

This study tested a program for women with high blood pressure after pregnancy. Participants monitored their blood pressure at home and reported it through an app. A nurse navigator helped adjust medications and coordinated follow-up care. The goal was to improve blood pressure c…

This study tested a program that helps pregnant women with gestational diabetes manage their condition with support from family members. 435 women in Vietnam took part. The goal was to see if this approach could improve health for both mothers and babies.

This study tested a program called Family Check-Up Heart, which adds heart-health coaching to regular home visits for new moms and their babies. About 150 mothers who had Medicaid and recently gave birth took part. The goal was to see if the program could help moms manage weight,…

This study tested whether hydroxytyrosol, a natural antioxidant found in olives, can reduce inflammation and oxidative stress in pregnant women with high blood pressure. 42 women took either a daily 10 mg hydroxytyrosol capsule or a placebo for 4 weeks. Researchers measured chang…

This study looked at 170 women with severe pre-eclampsia in the ICU to see which blood pressure drug—phentolamine or glyceryl trinitrate (GTN)—better protects kidney function. Pre-eclampsia can harm the kidneys, and GTN has been linked to kidney injury in some cases. The research…

This study tested whether trained community health workers visiting pregnant women at home could improve health for both mothers and children in a rural area of South Africa. The program focused on supporting women with HIV, depression, or alcohol use, and on improving child grow…

This study tested a drug called avelumab in 24 women with a rare pregnancy-related cancer (GTN) that did not respond to standard chemotherapy. The goal was to see if the drug could lower tumor markers (hCG) to normal levels and allow treatment to stop. Avelumab works by helping t…

This study tested whether Pilates or circuit exercise training could help lower blood pressure and improve cholesterol levels in 69 pregnant women with gestational hypertension. All women also received standard blood pressure medication. The exercises were done three times a week…

This pilot study tested whether a yogurt enriched with lactoferrin, a protein found in milk, could improve iron levels in 50 women with gestational diabetes. Half ate the special yogurt twice a day for two months, while the other half ate regular yogurt. The main goal was to see …

This completed trial tested whether sharing updated guidelines for diagnosing slow labor could reduce the number of C-sections in first-time mothers. Over 88,000 women at hospitals in Alberta took part. The goal was to lower C-section rates without increasing risks for mothers or…

This study looked at 200 women with eclampsia (a serious condition causing seizures during pregnancy) to see if giving magnesium sulphate into a vein (IV) or into a muscle (IM) works better to stop seizures from coming back. Women were randomly assigned to one of two treatment gr…

This study tested an online personalized program for pregnant women with obesity to help them gain the right amount of weight and reduce the need for delivery interventions like C-sections or forceps. Over 800 women participated, using a secure website to communicate with dietiti…

This study looked at 88 pregnant women whose water broke before labor started, comparing those who got labor-inducing gel right away versus those who waited 24 hours. The goal was to see which approach led to shorter labor and more vaginal deliveries. The findings could help guid…

This study tested whether tranexamic acid, a drug that helps blood clot, can safely stop vaginal bleeding in pregnant women with abruptio placenta (when the placenta separates from the womb too early). 116 women at 24 weeks or more of pregnancy received either the drug or a place…

This study looked at whether giving more red blood cell transfusions (liberal strategy) to extremely low birth weight babies (under 1000 grams) helps them survive without brain damage compared to a more restrictive approach. Over 1800 infants from NICUs were followed until 22-26 …

This study tested three football-based programs for teen girls in Zambia to improve HIV testing, birth control use, and mental health. Over 2,100 girls from 32 schools took part. The programs aimed to make it easier for girls to get sexual health services and stick with HIV treat…

This pilot study tested two common blood pressure medications—a combination pill of hydrochlorothiazide and lisinopril versus extended-release nifedipine—in 70 new mothers with high blood pressure after delivery. The goal was to see which pill controls blood pressure better in th…

This study looked at 60 women with preeclampsia having a C-section to find the best doses of two drugs (phenylephrine and norepinephrine) to prevent dangerously low blood pressure after spinal anesthesia. The goal was to identify doses that work in 90% of patients. The findings c…

This study tested whether placing two stitches instead of one around the cervix during an emergency can help women with a weak cervix carry their pregnancy longer. The trial included 81 women between 16 and 25 weeks of pregnancy whose membranes were bulging out. The goal was to s…

This study tested a medical device that filters a harmful protein called sFlt-1 from the blood of pregnant women with preeclampsia, a serious condition causing high blood pressure. The goal was to see if the treatment is safe and can help control the disease. The trial involved 2…

This trial tested a program where community health workers used a tablet app to screen pregnant women in rural India for anemia, high blood pressure, and diabetes. Over 3,400 women took part. The goal was to see if this screening and referral system could lower anemia rates and i…

This study looked at whether giving magnesium sulfate for 12 hours after delivery instead of the usual 24 hours is safe and effective for preventing seizures in women with mild preeclampsia. Researchers enrolled 200 women and compared the two treatment lengths. The goal was to se…

This study tested a simple technique called cystoinflation—filling the bladder with 200 mL of saline during surgery—to see if it prevents bladder injury in women with placenta accreta spectrum (PAS). 84 women were randomly assigned to receive the bladder fill or standard surgery.…

This large study tested whether the diabetes pill glyburide works as well as insulin shots for treating gestational diabetes in 914 pregnant women. The goal was to see if glyburide could prevent newborn complications like high birth weight, low blood sugar, and jaundice. If effec…

This trial is testing whether 3D ultrasound can diagnose placenta accreta spectrum more accurately than the standard 2D ultrasound with color Doppler. Placenta accreta is a serious pregnancy condition where the placenta grows too deeply into the uterine wall, which can cause seve…

This study is testing whether a simple blood test can help doctors tell apart two main causes of intrauterine growth restriction (IUGR) — a condition where a baby grows slower than expected in the womb. The test measures the ratio of two proteins, sFlt-1 and PlGF, which are linke…

This study looks at whether measuring the optic nerve sheath (the lining around the nerve connecting the eye to the brain) combined with blood tests for angiogenic factors can better diagnose severe pre-eclampsia in pregnant women. Pre-eclampsia is a serious condition that can ha…

This study uses a non-invasive ultrasound called transcranial Doppler (TCD) to measure blood flow in the brains of pregnant women with preeclampsia. Researchers will compare 50 women with preeclampsia to 50 healthy pregnant women to see if TCD can detect early signs of serious co…

This study looked at whether a 1-hour glucose test (using 50 grams of sugar) can accurately diagnose gestational diabetes, so pregnant women might not need the longer 3-hour test. Researchers analyzed results from 351 women with singleton pregnancies who had already completed bot…

This study tested whether a special ultrasound score (called VEXUS) can predict acute kidney injury in women with severe preeclampsia when they are admitted to the hospital. Researchers examined 70 women using Doppler ultrasound to check blood flow in key veins. The goal was to s…

This study looked at whether measuring homocysteine levels in the blood can help predict how severe preeclampsia will become in pregnant women. Researchers measured homocysteine in 70 critically ill preeclampsia patients and analyzed its link to complications. The goal is to see …

This completed study looked at whether measuring blood flow in the fetal lung artery using ultrasound can predict breathing difficulties in newborns. Researchers studied 86 pregnant women with severe preeclampsia between 28 and 37 weeks. The goal was to see if a specific ultrasou…

This study looked at whether a protein called Cadherin-6 in the blood of pregnant women could help predict preeclampsia, a dangerous condition involving high blood pressure. Researchers measured Cadherin-6 levels in 150 women between 15 and 20 weeks of pregnancy and tracked who l…

This study tested whether a blood test measuring the sFlt-1/PlGF ratio can help doctors decide the best care for pregnant people with suspected preeclampsia before 35 weeks. 84 participants were randomly assigned to have their care guided by the test or usual care. The goal was t…

This study looked at whether a substance in the blood called adropin can help identify placenta accreta spectrum, a serious condition where the placenta grows too deeply into the womb. Researchers measured adropin levels in 84 pregnant women—42 with the condition and 42 healthy—t…

This pilot study tested a new, noninvasive breath test to see if it could identify pregnant women at risk for gestational diabetes. Twenty pregnant women provided breath samples after drinking a special sugar solution, and the results were compared to standard blood tests. The go…

This completed study looked at whether certain molecules in the blood (kisspeptins and miRNAs) can help diagnose non-viable pregnancies, including ectopic pregnancies. Researchers collected blood samples from 433 women to measure these biomarkers. The goal is to develop a more ac…

This study tested whether Dex4 chewable tablets work as well as the standard sugary drink for diagnosing gestational diabetes in pregnant women. Thirty-one women who screened positive for gestational diabetes took both tests to compare blood sugar levels and side effects. The goa…

This study tested whether a special ultrasound using contrast dye can better diagnose placenta accreta, a condition where the placenta grows too deeply into the womb and can cause severe bleeding after birth. Researchers studied 80 pregnant women at high risk for this condition. …

This study tested a new wearable patch called TOCONAUTE that sticks to a mother's belly during labor. The patch measures the baby's heart rate and the mother's contractions, just like the standard monitors but without wires. Researchers compared the patch's readings to the usual …

This study compared continuous glucose monitoring (CGM) to the standard glucose challenge test for screening gestational diabetes in over 1,600 pregnant women. The goal was to see if CGM leads to better health outcomes for mothers and babies, such as fewer large babies or birth i…

This study looked at whether a protein called EG-VEGF in the blood of pregnant women could predict pre-eclampsia or poor fetal growth. Researchers took blood samples and performed ultrasound scans on 142 women early in pregnancy. The goal was to see if EG-VEGF levels could serve …

This study tested a small, portable ultrasound device (echOpen O1) for pregnancy follow-ups in Senegal, where access to standard machines is limited. 224 pregnant women were scanned with both the portable device and a regular ultrasound machine to see if the portable one could re…

This completed study of 6,608 pregnant women in China aimed to create a risk score to predict gestational diabetes mellitus (GDM) early in pregnancy. Researchers collected basic information, lab results, and diet/exercise data from hospital systems and questionnaires. The goal is…

This study looked at whether a blood test measuring the sFlt-1/PlGF ratio can help doctors decide if women with suspected pre-eclampsia need to be hospitalized. Pre-eclampsia is a serious pregnancy condition that can harm both mother and baby, but diagnosing it is tricky. The stu…

This study tested whether functional MRI can detect differences in oxygen flow in the placenta and fetus between healthy pregnancies and those with intrauterine growth restriction (IUGR). Pregnant women breathed pure oxygen while MRI scans measured the BOLD effect, a signal chang…

Women with class III obesity who gain too much weight during pregnancy face higher risks of diabetes, high blood pressure, cesarean delivery, and larger babies. Standard prenatal care often does not include nutrition counseling based on weight. This trial tests whether adding gro…

This trial tests whether a group prenatal care model that includes social services can improve maternal mental health and reduce preterm birth compared to standard individual care with added services. Pregnant women eligible for Medi-Cal in central California are randomly assigne…

This study tested whether adding a special 'pre-session'—which includes education about diabetes risks, motivational interviewing, and help solving barriers—could encourage more people to attend a national diabetes prevention program. The trial involved 483 adults at risk for dia…

This trial tests whether a structured antenatal education program can reduce cesarean section rates among first-time mothers in Turkey. Researchers will enroll 120 pregnant women at 28 weeks or more, with 40 receiving a 4-hour childbirth preparation class and 80 serving as contro…

This study is testing whether following a Mediterranean diet during pregnancy can reduce the chance of children developing allergies by age 2. Researchers are enrolling 276 healthy pregnant women (ages 20-35) who are at risk of having a baby with allergies. Participants receive p…

This phase 4 trial tests whether taking metformin daily before 20 weeks of pregnancy can reduce the risk of high blood pressure disorders, like preeclampsia, in pregnant women with type 1 diabetes. About 60 women will receive either metformin plus standard care or standard care a…

This pilot study tests whether offering multiple micronutrient supplements (MMS) directly at antenatal clinics in Botswana increases their use among pregnant women. The study will measure how well clinics adopt the program and whether it improves outcomes like weight gain, anemia…

This study tests whether screening women for type 2 diabetes while they are still in the hospital after giving birth can help catch the disease early and prevent it. About 116 women who had gestational diabetes will be randomly assigned to either early testing or usual care. The …

This study in Addis Ababa, Ethiopia, tests whether giving protein supplements only to pregnant women who are undernourished can prevent problems like low birth weight and stillbirth. Over 6,700 pregnant women are randomly assigned to receive supplements either universally or only…

This study tests whether limiting eating to a 10-hour window each day can lower the chance of developing gestational diabetes in pregnant women at high risk. Researchers will compare this approach to usual eating habits over 3 months in 240 women. The goal is to see if this simpl…

This study tests whether taking a daily vitamin D supplement (4000 IU) can lower the chance of preeclampsia returning in pregnant women who have had it before. Researchers will randomly assign 146 women to receive either vitamin D or a placebo from enrollment until 36 weeks of pr…

This study tested a phone-based health coaching program for pregnant women with a higher body mass index. The goal was to help them gain a healthy amount of weight during pregnancy and prevent problems like gestational diabetes and later obesity in both mothers and children. Over…

This large study tested whether giving tranexamic acid (TXA) during C-sections can prevent severe bleeding. Over 11,000 women received either TXA or a placebo right after delivery. The goal was to see if TXA reduces the need for blood transfusions or death. Results could change h…

This study looked at two approaches to giving iodine supplements to pregnant women. One group received a daily iodine pill from 14 weeks until delivery. The other group had their urine iodine tested first; only those with low levels got iodine, while others got an iron pill. The …

This study tested a group prenatal care program called TLC for obese women at high risk for gestational diabetes. Over 300 women joined small groups led by a healthcare provider and learned about nutrition, exercise, and healthy habits. The goal was to see if this approach could …

This study tested a program to help pregnant women with overweight or obesity avoid gaining too much weight. The program included setting goals, tracking weight, learning skills, and getting support from WIC counselors. 416 women from Philadelphia WIC took part, and researchers m…

This study tested whether giving intravenous iron to pregnant women who have low iron stores but not yet anemia can prevent them from becoming anemic and help their babies grow normally. 600 women took part. The goal is to see if a single IV dose works better than usual care.

This study tested whether taking a low-dose aspirin (160 mg) each night, starting before 16 weeks of pregnancy, could prevent pre-eclampsia and small babies in first-time mothers at high risk. Over 1,100 women with abnormal blood flow in the uterine artery were randomly assigned …

This study looked at how aspirin affects platelet function in 130 pregnant women at high risk for preeclampsia. Researchers measured platelet response and genetic factors to see if they could predict who develops high blood pressure disorders. The goal is to eventually personaliz…

This completed trial tested a program to increase COVID-19 vaccination among pregnant women. Over 6,900 participants were involved across OB/GYN practices. The program included training for healthcare providers, reminders, and feedback on vaccination rates. The goal was to see if…

This study tested a self-management app for women who had high blood pressure during pregnancy. 99 new mothers used the app to track their blood pressure, stress, and mood, or received usual care. The goal was to see if the app helps lower blood pressure and improve mental health…

This study tests whether a buprenorphine patch can reduce withdrawal symptoms when pregnant women with opioid use disorder start sublingual buprenorphine treatment. Forty participants will receive either a real patch or a sham bandage during the initial withdrawal period. Researc…

This trial explores whether two different internet-delivered programs can help pregnant women reduce stress, anxiety, and depression. One program teaches cognitive-behavioral stress management skills, while the other is a supportive group discussion. Researchers will measure chan…

This trial tests whether an 8-week mindfulness-based stress reduction program can help first-time pregnant women feel less depressed, improve their psychological well-being, and strengthen their attachment to their unborn baby. About 108 women in their first pregnancy, between 13…

This study looks at whether coloring mandalas can lower stress, anxiety, and pain in women who have a missed abortion (a pregnancy loss before 10 weeks). About 126 women will be randomly assigned to either color mandalas or receive standard care. Researchers will measure changes …

This trial tests whether an ultrasound-guided erector spinae plane block can reduce pain and the need for opioids during and after cesarean sections in women with placenta accreta, a condition where the placenta grows too deeply into the uterine wall. Participants will receive th…

This trial investigates whether combining electroacupuncture with stabilizing exercises can reduce pain and limit pelvic joint separation in pregnant women with symphysis pubis dysfunction. Sixty women between 25 and 28 weeks of pregnancy will either receive six weeks of electroa…

This study tests whether a gentle hands-on technique called myofascial release, combined with specific exercises, can reduce round ligament pain in pregnant women. The trial includes 70 women at 24 weeks of pregnancy who have this type of pain. One group receives the manual thera…

This study tests whether giving first-time mothers a written labor guide when they are admitted for labor induction helps them feel more in control during childbirth. Half the participants receive the guide, while the other half get standard counseling. Researchers measure percei…

This study tests whether eating fresh quince or applying acupressure (a non-invasive pressure technique) can reduce nausea and vomiting in pregnant women with mild to moderate morning sickness. Researchers will also measure effects on quality of life, stress, and self-care. The g…

This study tests whether using a virtual reality headset during placement of a cervical ripening balloon can reduce pain and anxiety for women undergoing labor induction. Sixty pregnant women will either receive standard care or standard care plus a VR experience. The goal is to …

This study looked at whether adding nonsteroidal anti-inflammatory drugs (NSAIDs) to standard pain relief is safe for women with severe preeclampsia after giving birth. 287 women participated, and researchers measured their blood pressure and need for blood pressure medication. T…

This study tested a device called the Hypotension Prediction Index (HPI) to see if it can reduce low blood pressure during planned C-sections. Low blood pressure after spinal anesthesia can harm both mother and baby. The device alerts doctors before blood pressure drops, so they …

This study investigates whether laughter yoga can lower stress and improve quality of life for pregnant women diagnosed with gestational diabetes. Participants will practice laughter yoga sessions that combine breathing exercises, clapping, and playful activities. The trial measu…

This study looked at whether adding supervised Pilates exercises and structured prenatal education to standard care could reduce depressive symptoms, low back pain, and labor pain in first-time mothers. 85 pregnant women participated, with some attending the program and others re…

This study tested a vibratory wristband worn on the inner wrist for 15-20 minutes to reduce nausea and vomiting in 240 pregnant women with hyperemesis gravidarum (severe morning sickness). The device stimulates a pressure point (P6) thought to calm the stomach. Researchers measur…

This pilot study tested a culturally tailored mindfulness program for 18 low-income, Spanish-speaking Latina pregnant women. The goal was to see if the program could reduce stress and improve markers of inflammation and blood sugar control. Participants were split into two groups…

This study tested a new monitoring system that predicts when a mother's blood pressure might drop dangerously during a planned C-section. The device uses a finger cuff to continuously measure blood pressure and an algorithm to warn doctors before a drop occurs. Researchers compar…

This study tested whether a four-week program of obstetric exercises could reduce depression, pregnancy complaints, and improve quality of life in 100 pregnant women in their third trimester. Half did the exercises with a physiotherapist, while the other half received standard pr…

This study looked at whether a simple intervention to relieve breast tenderness in late pregnancy could improve breastfeeding, reduce breast engorgement, and lower stress for new mothers. Researchers followed 160 healthy pregnant women from 36 weeks onward. The goal was to see if…

This study looked at whether giving birth in water (waterbirth) is better than a traditional land birth for low-risk, healthy women. Researchers compared pain medication use, labor length, breastfeeding rates, and satisfaction between the two groups. The goal was to see if waterb…

This study looked at whether exercising in the morning or evening helps control blood sugar better in pregnant women with gestational diabetes or glucose intolerance. 39 women walked or stepped for 30 minutes either after breakfast or after dinner. The researchers measured blood …

This study tested whether wearing virtual reality glasses during a routine postpartum uterine tone assessment could lower anxiety and pain while increasing comfort. 146 women within 24 hours of giving birth participated. Researchers measured pain with a visual scale and anxiety w…

This study tested a 5-week digital counseling program for 54 women who had a pregnancy loss within the past two months. The program focused on emotional support and coping skills. Researchers measured grief and stress levels before, right after, and up to 6 months later to see if…

This study tested two ways of giving epidurals to 102 pregnant women in labor: a standard method and a newer one called dural puncture epidural (DPE). The goal was to see which provides faster pain relief and better satisfaction. Results help doctors choose the best option for ma…

This pilot study tested whether giving two medications (mifepristone and misoprostol) at the same time helps women deliver faster after a nonviable second-trimester pregnancy, compared to misoprostol alone. Thirty women between 14 and 28 weeks pregnant who needed labor induction …

This study tested whether acupuncture or deep breathing exercises could help lower blood pressure in pregnant women with hypertension during their third trimester. Forty women aged 25-35 took part. The goal was to find safe, non-drug options for managing high blood pressure in pr…

This study tested a nurse-led education program for pregnant women with gestational diabetes. 71 women took part, with some receiving the program and others standard care. The goal was to see if the program improved healthy behaviors, self-confidence, and health beliefs, and redu…

This study tested whether an 8-week mindfulness-based cognitive therapy (MBCT) program can reduce stress, anxiety, and depression in pregnant women at risk for psychological distress. 84 women participated, with some receiving MBCT and others getting usual care. The goal was to u…

This study looked at whether mind-body exercises (like gentle movement and breathing) can lower stress, anxiety, and fatigue in pregnant women. 34 women in their second trimester were split into two groups: one did mind-body exercises, the other did relaxation exercises. The goal…

This study tested whether having a doula—a trained support person—before, during, and after delivery improves how Black birthing people feel about their care. 30 participants completed surveys about communication with their provider and overall care. The goal was to see if doula …

This study tested whether haptonomy—a gentle touch therapy with music—could lower risk perception, distress, and improve attachment in pregnant women who had previously lost a baby. 126 women in Turkey took part, half receiving five haptonomy sessions. Researchers measured change…

This study tested whether giving pregnant trainee doctors extra support—like a smart bassinet, wearable breast pump, 24/7 online perinatal care, and a faculty mentor—could reduce burnout and improve wellbeing. 156 pregnant residents and fellows from four hospitals were randomly a…

This study tested whether a hand massage technique called Su-Jok can reduce low back pain and improve comfort in pregnant women. 74 women with back pain at 32 weeks or more of pregnancy received the massage. Researchers measured pain and comfort using standard scales. The goal is…

This study tested whether a specific hand massage technique (seed therapy or su jok) can reduce nausea and vomiting and improve quality of life in pregnant women hospitalized with hyperemesis gravidarum, a severe form of morning sickness. Researchers enrolled 70 pregnant women an…

This study tested a mobile app called JUN that uses artificial intelligence to track symptoms and give timely advice to pregnant women. The goal was to see if the app helps women feel more confident in managing their health, especially those under criminal justice supervision lik…

This study looked at whether doing a mandala coloring activity could lower stress and fear of childbirth in women hospitalized with high-risk pregnancies. 149 pregnant women took part. The researchers measured their anxiety, stress, and fear levels before and after the activity.

This study looked at whether two sessions of hypnosis could lower anxiety in pregnant women with preterm premature rupture of membranes (PPROM). 60 women took part, with some receiving hypnosis and others standard care. The goal was to see if hypnosis helps reduce anxiety and imp…

This study tested whether kinesiotaping, a drug-free elastic tape, can relieve pelvic girdle pain in pregnant women. 72 participants wore the tape for five days, and researchers measured pain levels before and after. The goal was to see if this simple, no-side-effect approach cou…

This study looked at whether exercising before or after lunch is better for controlling blood sugar in women with type 1 diabetes, including those who are pregnant. Twenty women participated, and researchers measured how much time their blood sugar stayed in a healthy range over …

This study compared using a cervical balloon catheter (a soft tube with a balloon) to prostaglandin drugs for inducing labor in 44 women who had a previous C-section. The goal was to see if the balloon method is safer and just as effective. The trial is now complete, and results …

This study tested a non-drug treatment called Personalized Integrated Chronotherapy (PIC) for depression during pregnancy and after childbirth. 120 pregnant women with major depression were randomly assigned to receive either usual care (medication or therapy) or PIC plus usual c…

This study looked at whether diaphragmatic breathing exercises could help pregnant women with low back pain. Fifty-eight women between 19 and 29 weeks pregnant did breathing exercises twice a day for six weeks. Researchers measured pain, disability, balance, and quality of life t…

This pilot study looked at whether drinking whey protein before eating carbohydrates could help control blood sugar spikes in pregnant women. Twenty-one pregnant women without diabetes took part. They had glucose tests with and without whey protein to compare blood sugar and insu…

This study looked at whether a regular stretching routine could improve heart health in pregnant women with obesity. 224 women were assigned to either a stretching program or usual care (moderate exercise). The researchers measured blood pressure and other heart-related markers f…

This study tested whether motivational interviewing, a counseling approach, could help pregnant women with gestational diabetes feel more confident managing their health and improve their quality of life. 72 first-time pregnant women participated. The results may show if this sim…

This study looked at two techniques for removing extra amniotic fluid in pregnant women with polyhydramnios (too much fluid). One method uses a syringe to manually pull out fluid, while the other uses a continuous suction machine. Researchers measured pain, fluid volume removed, …

This study compared two medications, norepinephrine and phenylephrine, for treating low blood pressure during spinal anesthesia in C-sections. 46 women were randomly given one of the two drugs when their blood pressure dropped. Both drugs worked well, but norepinephrine kept the …

This observational study investigates the role of hormonal and metabolic disorders in the development of gestational diabetes mellitus (GDM). Researchers are analyzing data from over 600 pregnant women to identify risk factors and markers that could predict adverse outcomes for b…

This study compares three ways of teaching midwifery students about preeclampsia and eclampsia: a digital game, a simulation, and traditional lectures. The goal is to see which method boosts knowledge, motivation, and attitude the most. 120 fourth-year midwifery students will tak…

This study looks at whether using a mobile health app (called Penelope) is a cost-effective way to manage high blood pressure disorders during pregnancy. About 250 pregnant women at risk for conditions like preeclampsia will either use the app or track their health on paper. Rese…

This study looks at whether a continuous glucose monitor (CGM) can provide better insight into blood sugar patterns in pregnant women at risk for gestational diabetes than the usual oral glucose tolerance test (OGTT). Researchers will give 400 high-risk pregnant women a CGM senso…

This study aims to adapt a program called Staying Healthy After Childbirth (STAC) for Black women and birthing persons. Researchers will work with community organizations and advisory boards to identify barriers and facilitators to implementation. The goal is to make the program …

Researchers at KK Women's and Children's Hospital are studying whether the timing of meals and snacks during pregnancy relates to blood sugar levels. About 300 pregnant women in Singapore, between 18 and 21 weeks gestation, will keep food diaries and use a food record app. The te…

This study looks at whether early-onset preeclampsia (a serious pregnancy condition) affects the size of two brain areas in the fetus: the fornix and hippocampus. Researchers will use ultrasound to measure these areas in 84 pregnant women—half with early-onset preeclampsia and ha…

This pilot study tests whether providing food boxes and extra money for healthy groceries can reduce food insecurity and improve birth outcomes for pregnant people on Medicaid. About 124 participants will receive either food delivery or financial support, along with recipes and h…

This study tested whether a very low energy diet (800 calories a day using meal replacements) before pregnancy could improve the health of obese women and their babies. 147 women participated, including those with obesity and healthy-weight women for comparison. Researchers measu…

This observational study looks at health data from about 10 million U.S. birth records to find the safest amount of weight gain during pregnancy for women with obesity. Current guidelines recommend the same 5 to 9 kg gain for all, but obesity has different levels of severity. Res…

This study looks at why babies born with restricted growth (IUGR) have a higher risk of childhood obesity. Researchers will track 400 mother-infant pairs for two years, analyzing T-cell changes and DNA methylation. The goal is to uncover early biological signs that could lead to …

This study asks parents who have lost a child during pregnancy or birth to share their experiences and needs. Researchers will use interviews, focus groups, and workshops to understand what parents go through. The goal is to develop recommendations for healthcare professionals on…

This pilot study is testing whether a noninvasive ultrasound device, called USCOM, can measure how well the heart is pumping blood in pregnant people who have just been diagnosed with fetal growth restriction (FGR). FGR means the baby is smaller than expected, and this condition …

This study tests whether giving gynecologic cancer patients a list of questions to ask their doctor improves their confidence, reduces distress, and builds trust. About 70 adults with newly diagnosed or suspected gynecologic cancer will either receive the question list or usual c…

This study explores whether alternative biomarkers, such as glycated albumin and glycated serum protein, can better track glucose control in pregnant women with diabetes and predict the risk of complications in their newborns. Researchers will collect blood samples from participa…

This large observational study across multiple African sites tracks pregnant women who use antimalarial drugs, especially in the first trimester. The goal is to assess whether these medications are linked to miscarriage, stillbirth, or major birth defects. By following thousands …

This study is observing 66 pregnant women at high risk for preeclampsia to see if changes in their platelets (blood cells involved in clotting) can predict pregnancy complications. Researchers will collect blood samples before and after starting daily low-dose aspirin. The goal i…

This study tests whether a family-centered developmental care program, called NIDCAP, can improve brain and behavior outcomes in preterm infants born with severe intrauterine growth restriction. The intervention involves weekly observations of each infant's behavior, with persona…

This study examines whether placentas from pregnancies with intrauterine growth restriction (IUGR) have different levels of certain progesterone receptors compared to healthy pregnancies. Researchers will analyze placental tissue collected after delivery from 90 women. The goal i…

This study looks at whether substances produced by gut bacteria, called TMAO, can help predict high blood pressure during pregnancy. Researchers will track 200 pregnant women by collecting blood and urine samples throughout their pregnancies. The goal is to find early warning sig…

Women who become pregnant after weight-loss (bariatric) surgery have a higher chance of delivering smaller-than-expected babies. This study tests whether tracking blood sugar fluctuations with a continuous glucose monitor during each trimester can help predict which babies will b…

This study tested whether a pop-up alert in electronic health records could increase doctors' recommendations for low-dose aspirin in pregnant women at high risk for preeclampsia. Over 800 women were included, and the alert was shown during prenatal visits. The goal was to see if…

This study looks at whether a blood gas measurement called base excess differs between pregnant women with severe preeclampsia and those with normal blood pressure. Researchers will test 100 women before delivery to see if abnormal base excess levels are linked to more severe dis…

This study investigates whether women who had high blood pressure during pregnancy (hypertensive disorders) show differences in brain health in midlife compared to those with normal pregnancies. Participants undergo MRI scans, blood tests, cognitive assessments, and sleep monitor…

This study looks at how lung ultrasound can help find lung issues early in women who are critically ill due to pregnancy complications or gynecologic cancer. Researchers will check for different lung ultrasound patterns and see if they relate to patient outcomes like death or nee…

This study tests a smartphone app designed to help African American and Spanish-speaking patients recognize warning signs of pregnancy-related death. Participants choose symptoms they are having and get advice on when to call a doctor or go to the emergency room. The goal is to s…

This study follows thousands of pregnant women in France who had or likely had COVID-19 during pregnancy or shortly after giving birth. Researchers track health problems in both mothers and newborns up to 12 weeks after delivery, using medical records and questionnaires about men…

This study examines whether two specific ultrasound measurements—the ratio of the transverse cerebellar diameter to abdominal circumference and the ratio of mid-thigh circumference to femur length—can more accurately estimate gestational age in both healthy and growth-restricted …

This study looks at how the womb lining heals after different types of womb-sparing surgery for placenta accreta, a serious pregnancy condition where the placenta grows too deeply into the womb wall. Researchers will use a small camera (hysteroscopy) three months after surgery to…

This study looked at 50 women aged 30–50 who had a cervical conization (a cone-shaped biopsy) to treat abnormal cervical cells. Researchers measured blood flow in the uterine artery before and one month after surgery using Doppler ultrasound. The goal was to see if the surgery ch…

This study looked at the health and lifestyle habits of 143 pregnant women in Baton Rouge during their third trimester. Participants filled out questionnaires about their eating, physical activity, sleep, and overall well-being. The goal was to gather information, not to test a t…

This study follows up on 370 mothers and their children who were part of a larger trial testing metformin for gestational diabetes. Researchers want to see if taking metformin during pregnancy reduces the risk of diabetes, obesity, and heart problems in mothers up to 10 years lat…

This study looks at whether women who had a cervical procedure called LEEP (loop electrosurgical excision procedure) before age 25 face higher risks in future pregnancies, such as preterm labor or early rupture of membranes. Researchers reviewed records of 115 women who had LEEP …

This study looked at whether using concept maps—diagrams that show how ideas connect—helps third-year medical students learn and remember information better. 26 students were split into three groups: one with no concept map, one with a map made by the teacher, and one where stude…

This study compared two artificial intelligence (AI) models to the standard Hadlock formula for estimating fetal weight from ultrasound scans. Researchers analyzed scans from 283 pregnant women between 24 and 42 weeks of pregnancy. The goal was to see if AI could be more accurate…

This study looked at how often a harmless condition called deciduosis appears during C-sections. Researchers examined 31 women and found that about 10% had this benign lesion, which was linked to abdominal pain during pregnancy. The goal was to better understand how common it is …

This study tested a training program for prenatal healthcare providers to help them use medication-assisted treatment (MAT) for opioid use disorder during pregnancy. Researchers looked at data from over 1,000 patients to see if the program increased use of MAT and improved health…

This study looked at whether a 15-20 minute educational program helps pregnant women decide to take a glucose test for gestational diabetes. 199 women between 24-28 weeks of pregnancy took part. Half got standard advice, the other half got a structured video and guidebook. The re…

This study tested a new care plan for 100 low-risk mothers and their newborns, allowing them to go home within 24 hours after a normal vaginal delivery. Participants received daily visits from a midwife for the first three days and used a special mobile app to stay in touch with …

This study looked at brain activity in pregnant women with opioid use disorder who were taking medication therapy. Researchers compared their brain scans to those of healthy pregnant women to see if there were differences. The goal was to learn more about how the body processes t…

This study looked at 100 pregnant women with gestational diabetes to see if they were taking the recommended amount of iodine. Iodine is important for both mother and baby, and health authorities suggest supplements during pregnancy. The goal was simply to find out if these women…

This completed study examined levels of certain proteins and growth factors in the placentas of 48 women with placenta previa or placenta percreta during the third trimester. Researchers measured substances like decorin, laminin, and collagen in placental tissue and blood samples…

This study tested whether a specific brand of prenatal multivitamin (Ritual) improves nutrient levels in pregnant women and their babies compared to another over-the-counter brand. About 80 pregnant women took one of the two vitamins throughout pregnancy, and researchers measured…

This study looked at whether pregnant women would accept using a vibrating relaxation tool to help with pain. 32 pregnant women were asked to use the tool at least twice. The goal was to see if this approach is worth studying further, not to prove it works.

This study looked at whether women with different types of gestational diabetes respond differently to meals with varying amounts of carbs, protein, and fat. Nineteen women with gestational diabetes wore a continuous glucose monitor and ate two test meals. The goal was to see if …

This study tested a new way to help women with heart risks like high blood pressure or diabetes get better care after giving birth. Researchers interviewed new moms to understand what makes it hard to attend follow-up visits, then designed a coordinated care system. They tested i…

This study looked at whether special ultrasound measurements of the baby's kidney and placenta can help predict health problems in newborns. Researchers compared 114 pregnant women with and without preeclampsia. The goal was to see if these scans could warn doctors about complica…

This study looked at how melatonin, a hormone known for sleep and as an antioxidant, changes during pregnancy. Researchers measured melatonin and its main byproduct in the blood of 60 women across each trimester. The goal was to gather basic information to help design larger stud…

This completed study looked at two new ways to understand why some labors slow down or stall (called labor dystocia). Researchers measured lactate levels in amniotic fluid and electrical signals from the uterus in 42 healthy women giving birth at term. The goal was to gather info…

This study tested a special nursing program that teaches pregnant women with preeclampsia about climate-related health risks, like heat and pollution. 104 women took part, with half receiving the program plus usual care and half receiving usual care alone. The goal was to see if …

This study looked at how babies suck on bottle nipples with different hole sizes. Researchers wanted to see if mothers who lost weight before pregnancy had babies with different sucking patterns. Ten mothers and their infants took part. The goal was to learn more about infant fee…

This study looked at how two hormones that rise during pregnancy—estradiol and cortisol—affect the way the body breaks down THC, the main active ingredient in cannabis. Fourteen healthy women of childbearing age took part. Researchers measured THC levels in the blood after taking…

This study tested whether playing recordings of a mother's voice to preterm babies in the NICU helps their brain and language development. Researchers enrolled 57 preterm infants born between 24 and 31 weeks. The goal was to see if this simple, non-invasive intervention could imp…

This completed study investigated why low-dose aspirin helps prevent preeclampsia in some high-risk pregnant women but not others. Researchers took blood samples from 35 women at four points during pregnancy to study their immune cells, particularly neutrophils. The goal was to i…

This study looked at 89 obese pregnant women to find out how common sleep apnea is and whether it is linked to high blood pressure, preeclampsia, or poor fetal outcomes. Participants had a sleep test (polysomnography) to detect apnea. The goal was to understand the connection and…

This study looked at how pregnancy changes the levels of the HIV drug doravirine in the blood. Seven pregnant women living with HIV took a single dose of doravirine during their second and third trimesters, and again after giving birth. The goal was to find the right dose for pre…

This completed study followed over 1,100 pregnant women in Guangzhou to see how their diet and nutrition during and after pregnancy relate to blood sugar problems like gestational diabetes. Researchers also tracked the children's growth, brain development, and allergies up to age…

This study followed over 2,000 pregnant women to measure their blood sugar levels throughout pregnancy. The goal was to see how glucose patterns relate to gestational diabetes and whether the baby is born larger than normal. Researchers used continuous glucose monitors and standa…

This study tested a program called OPTIMIZE that uses a checklist and patient navigators to help Black pregnant women get better care during and after pregnancy. About 548 women took part across several clinics. Half the clinics used the program, and half provided standard care. …

This study looked at whether home visits by healthcare providers during pregnancy can improve mothers' knowledge, increase vaginal births, boost breastfeeding confidence, and reduce postpartum depression. Sixty-four first-time mothers with low-risk pregnancies took part. The appr…

This study looked at whether a 4-week resistance training program is doable for women who had pregnancy complications like preeclampsia or preterm birth. Seven new moms participated, and researchers measured how well they stuck with the exercises and how they felt about them. The…

This completed study looked at why some pregnant women in France choose not to join randomized clinical trials about pregnancy and childbirth. Researchers surveyed 526 women to find out what factors — like age, education, or how the study was explained — might influence their dec…

This completed study looked at 36 pregnant women to understand why the membranes around the baby break too early (PPROM). Researchers measured certain proteins called syndecans in the mother's blood and in the placenta and amniotic membrane after birth. The goal was to find clues…

This completed study observed 72 pregnant women with HELLP syndrome in the ICU. Researchers tracked daily changes in platelets, liver enzymes, and lactate dehydrogenase before and after delivery. The goal was to understand how these biological markers evolve, not to test a treatm…

This study looked at whether using a continuous glucose monitor (CGM) is better than standard finger-prick checks for managing blood sugar in pregnant women with type 2 diabetes. Sixteen women participated, and researchers measured how well blood sugar stayed in a healthy range a…

This study looked at how emergency general surgery affects pregnant women and their unborn babies. Researchers planned to follow pregnant women who needed surgery for problems like appendicitis or gallbladder disease. The goal was to learn more about the safety of these surgeries…

This study measured a substance called preptin in the umbilical cord blood of 72 newborns. Researchers compared levels in babies with low or high birth weight to those with normal weight, and also looked at babies born to mothers with diabetes. The goal was to see if preptin leve…

This study examined 33 preterm babies born before 30 weeks to mothers with preeclampsia. Researchers measured certain proteins in the mother's blood, umbilical cord blood, and amniotic fluid to see if they were linked to a lung condition called bronchopulmonary dysplasia (BPD). T…

This study collected blood samples from 236 pregnant women with and without preeclampsia. The goal was to test a new approach that filters out a protein called sFlt-1 from the blood, which may help restore normal blood vessel function. The research is a first step toward a possib…

This study looked at over 2,100 people with listeriosis, a serious foodborne infection that can cause blood infections, brain infections, and pregnancy complications. Researchers collected data to find out which clinical, biological, and genetic factors make someone more likely t…

This study looked at whether iron supplements improve how well vaccines work in pregnant women with anemia (low iron). Researchers compared their immune responses to tetanus, diphtheria, and COVID-19 vaccines against women without anemia. The goal was to see if correcting iron de…

This study followed 81 pregnant women whose babies were growing slowly in the womb (a condition called IUGR). Researchers used ultrasound to measure blood flow in a key fetal blood vessel every week during the third trimester. They then checked if these measurements could predict…

This study looked at pregnant women being treated for opioid use disorder with two different forms of buprenorphine: a monthly shot and a daily tablet. Researchers measured drug levels in the mother's blood and checked the baby's heart rate to see how each treatment affected both…

This study looked at 71 babies born to mothers who took either a monthly injection or a daily tablet of buprenorphine for opioid use disorder during pregnancy. Researchers measured the babies' thinking, language, and motor skills using a standard child development test. The goal …

This study looked at how much vitamin D pregnant women need to reach healthy levels. 105 women at risk of deficiency took either 20 or 40 micrograms of vitamin D daily throughout pregnancy. Researchers measured their vitamin D levels and other health markers to see which dose wor…

This study used MRI scans to measure blood flow in the placenta of 135 women undergoing pregnancy termination for fetal reasons between 16 and 32 weeks. The goal was to create a set of normal reference ranges for placental perfusion, which could help doctors identify when the pla…

This study looked at pregnant women at high risk for placenta accreta, a serious condition where the placenta grows too deeply into the womb. Researchers wanted to find out which factors, such as how the condition is diagnosed and managed, affect the mother's health. Over 600 wom…

This study tested whether a simple pocket booklet and regular training for doctors and midwives could reduce stillbirths and improve care during childbirth. Over 65,000 women and their newborns were followed across five hospitals in Tanzania. The goal was to see if practical, low…

This study tested whether pregnant women can have their pre-birth anesthesia consultation through a video call instead of coming to the hospital. 60 women participated, using a telemedicine cabin or cart near their home. The goal was to see if the video assessment of the airway i…

This study tested a shared decision-making tool called NEST to help pregnant women understand and choose noninvasive prenatal testing (NIPT). Over 600 pregnant women participated, comparing those who used the tool with those who received usual care. The goal was to see if the too…

This study looked for proteins in the blood that could tell doctors early on whether a broken arm bone is healing well or might lead to a nonunion (where the bone doesn't heal). Researchers studied 45 adults with simple humerus fractures treated without surgery. They checked bloo…

This study looked at 150 women who had a rare heart condition called peripartum cardiomyopathy (heart failure around childbirth) that led to cardiogenic shock (the heart can't pump enough blood). Researchers observed their long-term health and the treatments they received. The go…

This study looked at whether combining virtual simulation with hands-on practice helps midwifery students learn better than virtual training alone. Thirty-two students were split into two groups to practice managing severe preeclampsia. The goal was to see if the combined approac…

This study looked at how giving IV fluids during a C-section affects heart function in women with preeclampsia. Researchers used ultrasound to measure heart output in 34 women. The goal was to better understand how to manage fluids safely in these patients.

This study looked at how much methionine, a building block of protein, pregnant women need during early and late pregnancy. Researchers tested 69 healthy pregnant women using special diets and breath tests. The goal is to improve current dietary recommendations, which are based o…

This completed study compared the heart effects of two drugs, oxytocin and carbetocin, given to prevent bleeding after childbirth. Researchers measured a heart injury marker (troponin I) in 240 healthy pregnant women after delivery. The goal was to see if carbetocin might be less…

This study looked at how obesity might affect the cells in the uterus that help with labor. Researchers took blood and uterine tissue samples from 38 women having C-sections, some with normal weight and some obese. They wanted to see if certain cells and chemicals in the blood co…

This study involved 40 pregnant women whose babies were not growing well (fetal growth restriction). Researchers wanted to see if a single session of moderate exercise would change the baby's well-being. They measured the baby's health using ultrasound before and after the exerci…

This study tested whether people with diabetes can use a smartphone game to monitor their vision at home, instead of always going to the clinic. 55 participants at high risk for diabetic retinopathy played vision games on their phones for 6 months. The goal was to see if people w…

This study looked at 1,000 women who gave birth at age 45 or older to understand the risks and complications they face. Researchers examined issues like preterm birth, delivery complications, and how long mothers stayed in the hospital. The goal was to gather information to help …

This completed observational study looked at 150 women to see how different types of fibroid removal surgery (hysteroscopic, laparoscopic, or laparotomic) affect pregnancy outcomes. It compared women who had surgery with those who did not, and also looked at whether surgery durin…

This study looked at 40 women to see how gestational diabetes changes hormones and nutrients in breast milk. Women with diabetes received personalized nutrition advice during pregnancy. After birth, researchers measured hormones and milk content. The goal is to learn more about h…

This study looked at two natural cell processes—autophagy (cell cleaning) and apoptosis (cell death)—in 97 pregnant women. Researchers wanted to see how these processes vary in normal pregnancies and in women at risk for complications. The goal was to understand the balance betwe…

This study followed 300 pregnant women to understand why some develop mood disorders like depression or bipolar episodes after giving birth. Researchers collected genetic, hormonal, and environmental data to find patterns that could predict these episodes. The goal is to better i…

This study looked at whether viral infections and diabetes in pregnant women are linked to congenital heart defects in their babies. Researchers analyzed blood and stool samples from 114 women to detect viruses and immune responses. The goal was to gather knowledge for future lar…

This study looked at 186 pregnant women with type 1 or type 2 diabetes to understand how fats in the blood relate to baby birth weight. Researchers measured blood fats, diet, and placenta genes. The goal is to find new ways to prevent babies from being born too large, which can c…

This study looked at why pregnant women tend to get more severe flu but not worse COVID-19. Researchers collected nasal brush samples and blood from 48 pregnant and non-pregnant women to compare how their immune systems respond to these viruses. The goal is to understand the prot…

This completed study followed 255 women with gestational diabetes to see if simple blood tests during pregnancy could predict who will develop type 2 diabetes after giving birth. Researchers measured three markers (CRP, MDA, and adiponectin) and checked glucose tolerance three mo…

This study tested a new, noninvasive device that uses light to monitor blood flow and oxygen in the brains of extremely premature babies. Researchers followed 100 infants born before 29 weeks to see if the device could detect problems linked to brain bleeding. The goal is to give…

This study looked at how the antibiotic amoxicillin works in pregnant women to help prevent passing syphilis to their babies. Researchers measured drug levels in the blood of 13 pregnant women during the second and third trimesters and after birth. The goal was to find the right …

This completed study looked at whether a blood test for a substance called ADMA can measure blood vessel health in children with growth hormone deficiency or those born small for their age. Researchers compared ADMA levels to ultrasound measurements of artery function in 23 child…

This study looked at how certain immune cells (neutrophils) form web-like structures in women with preeclampsia compared to those with normal pregnancies. Researchers analyzed stored blood samples from 26 women to understand two different ways these webs are made. The goal was to…

This study measured certain proteins (histones and HMGB1) in the blood of 115 pregnant women to see if they could help detect placenta-related complications like pre-eclampsia. Researchers compared women with normal pregnancies, those with complications, and healthy non-pregnant …

This study followed over 1,500 women who had pregnancy losses and were tested for antiphospholipid syndrome (APS) and other clotting disorders. Researchers compared cancer rates among women with APS, those with other clotting gene changes, and those with no clotting issues. The g…

This study looked at 210 women who had gestational diabetes during pregnancy, comparing them to similar women without it about 8 years later. Researchers measured blood sugar, insulin, weight, and lifestyle factors to understand who develops type 2 diabetes. The goal was to find …

This study followed 168 women with Multiple Sclerosis who were pregnant or planning pregnancy. Researchers collected information through phone interviews every three months during pregnancy and tracked the baby's growth for up to three years after birth. The goal was to understan…

This study tested whether a special ultrasound scoring system (Placenta Accreta Index) can help doctors decide the safest type of surgery for pregnant women with placenta accreta, a condition where the placenta grows too deeply into the womb. Researchers studied 154 women with pl…

This completed study investigated levels of a protein called CD71 in placentas from 39 women with preeclampsia and 39 healthy pregnant women. Researchers also looked at newborn outcomes. The goal was to better understand how preeclampsia develops. No treatment was tested; this is…

This study looked at 850 pregnant women with gestational diabetes to see if very tight blood sugar targets or moderate targets lead to better outcomes for mothers and babies. It also explored how different targets affect genes in the baby. Women were assigned to lifestyle changes…

This study measured the amount of free-floating DNA and nucleosomes in the blood of 137 women to see if these levels differ between those with pregnancy complications (like preeclampsia or blood clots) and healthy women (both pregnant and non-pregnant). The goal was to better und…

This study looked at whether low vitamin D levels in the first trimester of pregnancy are linked to developing preeclampsia later on. Researchers measured vitamin D in over 3,000 pregnant women in France. The goal was to understand how common vitamin D deficiency is and if it rel…

This study looked at whether measuring fructosamine levels in the blood can help predict which women with gestational diabetes will need insulin. Researchers enrolled 200 pregnant women and measured their fructosamine levels. The goal was to see if this test could guide treatment…

This study looked at 100 preterm babies who were small for their gestational age and needed IV nutrition. Researchers compared two ways to calculate their nutritional needs: using the baby's actual birth weight versus using a corrected weight (the weight they would be at the 10th…

This study looked at 500 women who had gestational diabetes during pregnancy. They took a glucose test 4 to 12 weeks after giving birth to see how many had type 2 diabetes, impaired glucose tolerance, or impaired fasting glucose. The goal was to compare women diagnosed with gesta…

This study tested a new prenatal care model that includes fathers. 216 young couples participated in co-parenting education, parenting classes, and job skills training. The goal was to see if this approach could improve relationships and prepare parents for their baby's arrival.

This study tested a new, non-invasive device that uses light to measure a baby's oxygen levels through the mother's belly during labor. 35 women in labor participated. The device was used only for research and did not guide any medical decisions. The goal was to see if the device…

This study tested a training program for labor and delivery providers in Tanzania to reduce HIV stigma during childbirth. The training used simulations and hands-on learning to help providers offer more respectful care. Researchers compared how women rated their care before and a…

This study surveyed 145 women with migraines who were pregnant between 2019 and 2021. It compared pregnancy and baby health between those who used the Nerivio device for migraine attacks and those who didn't. The goal was to see if using Nerivio during pregnancy is safe for both …

This study examined how well the heart relaxes between beats in 80 pregnant women—40 with preeclampsia and 40 healthy. Researchers used ultrasound to measure heart function. The goal was to see if preeclampsia is linked to early signs of heart strain, which could help doctors cat…

This completed study looked at why some pregnant women chose not to take part in a larger trial on early screening for pre-eclampsia, a serious pregnancy condition. Researchers surveyed 472 women to find factors linked to refusal and to understand their reasons for saying yes or …

This completed trial compared two training programs for first-time pregnant women: one focused on preparing for the maternal role, and the other on mindfulness-centered occupational therapy. The study included 74 women between 14-27 weeks of pregnancy and followed them after birt…

This completed study interviewed 28 women with a history of bulimia or binge-eating disorder about their pregnancy and postpartum experiences. Researchers aimed to understand how these women cope with body changes and interact with healthcare services. The goal is to improve care…

This study tested whether a special brain MRI could predict which unborn babies with poor growth (intrauterine growth restriction) will have health problems after birth. Researchers scanned 82 fetuses before 32 weeks of pregnancy and compared the results to their health at delive…