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Pilot study tracks melatonin in pregnancy for future biomarker research

NCT ID NCT03014245

Knowledge-focused Sponsor: University of Aberdeen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how melatonin, a hormone known for sleep and as an antioxidant, changes during pregnancy. Researchers measured melatonin and its main byproduct in the blood of 60 women across each trimester. The goal was to gather basic information to help design larger studies on whether melatonin could be a marker for pregnancy complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Nov 2016

Finished

May 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy women pregnant with first baby (singleton) presenting for first trimester scan and healthy non-pregnant women of child bearing age.

Ages

16 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Pregnant subjects * Primigravid women (in their first pregnancy) * Singleton pregnancy * Aged 16-45 * Taking no regular medication other than pregnancy related vitamins or supplements * First trimester (FVS) ultrasound scan reported as normal Non pregnant subjects * Non pregnant women * Aged 16-45 * No chronic health issues and not taking any medication Exclusion Criteria: Pregnant subjects * Pregnancy non-viable on scan * Twins or higher multiple pregnancies * Outside age range * Diabetes or pre-existing hypertension, chronic kidney disease or known autoimmune disorder Non pregnant subjects * Male * Outside age range * Chronic health complaint/taking medication * Recent blood donation over 1 unit

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pregnancy transient hypertension

Contacts and locations

Locations

  • Aberdeen Maternity Hospital (NHS Grampian)

    Aberdeen, Aberdeenshire, AB25 2ZB, United Kingdom