Study examines pregnancy after fibroid surgery
NCT ID NCT06474065
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed observational study looked at 150 women to see how different types of fibroid removal surgery (hysteroscopic, laparoscopic, or laparotomic) affect pregnancy outcomes. It compared women who had surgery with those who did not, and also looked at whether surgery during pregnancy made a difference. The goal was to gather information on complications and outcomes, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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150 people
The number who actually took part.
- Started
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Jun 2024
- Finished
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Dec 2025
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients to submit to myoemctomy, are divided in three major groups: * Group A: myomectomy outside of pregnancy-A1 hysteroscopic; A2 laparoscopic; A3 laparotomy * Group B: myomectomy during CS: B1 trans-endometrial; B2 serosal * Group C: control group with repeated CS
- Ages
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25 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. women of reproductive age (up to 45 yrs)-all groups 2. women who had myomectomy (group A and B)/CS (group C) at least two years before the enrolment 3. myomas 30 mm in size and larger (groups A and B) 4. Study groups: myomectomy performed as hysteroscopic/laparoscopic/laparotomic myomectomy or cesarean myomectomy, both using transendometrial or serosal approach: gravida 2 para 2 or gravida 1 para 1 \[groups A1, A2, A3 and groups B1 and B2\] 5. Control group: women who had cesarean section in their second pregnancy-para 2 gravida 2, at least two years after the CS \[group C\] Exclusion Criteria: 1. any previous surgery on reproductive organs except myomectomy 2. any additional operation during cesarean myomectomy procedure except cesarean section 3. history of endometriosis or PID 4. coagulation disorders 5. previous treatment for any malignant disease 6. previous GTD 7. premature ovarian failure or any kind of ovarian insufficiency necessitating oocyte donation 8. systemic diseases: IBD, MS, DM
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Andrea Tinelli
Lecce, Le, 73100, Italy
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Other studies related to the condition(s) this trial covers.
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