New study pinpoints safer blood pressure dosing for moms with preeclampsia
NCT ID NCT06158022
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 36 times
Summary
This study looked at 60 women with preeclampsia having a C-section to find the best doses of two drugs (phenylephrine and norepinephrine) to prevent dangerously low blood pressure after spinal anesthesia. The goal was to identify doses that work in 90% of patients. The findings could help doctors manage blood pressure more precisely during delivery, reducing risks for both mother and baby.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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General hospital of Ningxia University
Yinchuan, Ningxia, 750004, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Phenylephrine and norepinephrine (vasopressors to raise blood pressure)
What this could lead to
If successful, this could establish precise dosing guidelines to prevent dangerous drops in blood pressure during C-section in women with preeclampsia, improving safety for mothers and babies.
What could go wrong
This is a small, completed dose-finding study (60 participants), not a large trial. The results may not apply to all patients or settings, and the drugs themselves can cause side effects like slow heart rate.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.