Simple blood test may spot preeclampsia risk before symptoms appear
NCT ID NCT07467226
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a protein called Cadherin-6 in the blood of pregnant women could help predict preeclampsia, a dangerous condition involving high blood pressure. Researchers measured Cadherin-6 levels in 150 women between 15 and 20 weeks of pregnancy and tracked who later developed preeclampsia. The goal is to find a simple test that identifies at-risk women early, so steps like low-dose aspirin can be started to reduce harm.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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150 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Peripheral venous blood samples will be collected between 15-20 weeks of gestation. Serum samples will be separated by centrifugation and stored at -80 ˚C until analysis.Serum concentrations of human cadherin-6 will be measured using an ELİSA method.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pregnant women aged 18-40 years * Singleton pregnancy * Gestational age between 15 and 20 weeks confirmed by first-trimester ultrasound * Availability of stored maternal serum samples * Written informed consent Exclusion Criteria: * Chronic hypertention * Pregestational diabetes mellitus * Renal disease * Multiple pregnancy * Smoking or alcohol use * Fetal structural or chromosomal anomalies * İmmunsuppressive treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Canan Soyer Çalışkan
Samsun, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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