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New MRI method maps healthy placental blood flow

NCT ID NCT01092949

Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study used MRI scans to measure blood flow in the placenta of 135 women undergoing pregnancy termination for fetal reasons between 16 and 32 weeks. The goal was to create a set of normal reference ranges for placental perfusion, which could help doctors identify when the placenta is not working properly. No treatments were tested; this was purely an observational study to gather baseline data.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better understand and detect placental insufficiency, potentially improving monitoring of high-risk pregnancies.
What could go wrong
This is an early observational study with no treatment involved. It only establishes reference ranges and may not directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

135 people

The number who actually took part.

Started

Feb 2010

Finished

Sep 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients undergoing TOP at 16 to 32 weeks will be offered to participate in this study.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women \> 18 years, * Undergoing TOP for fetal reason, * Informed signed consent. Exclusion Criteria: * Placental adhesion anomaly, * Growth restriction, * Contrast agent allergy, * Absent consent, * Contraindication of MRI or Gadolinium, * Renal insufficiency, * Placental abnormality at pathological examination.

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Conditions

The condition(s) this trial relates to.

placental insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Placental insufficiency

Contacts and locations

Locations

  • Necker Enfants Malades

    Paris, 75015, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.