New doppler study aims to spot fetal distress earlier in Growth-Restricted pregnancies
NCT ID NCT07676708
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study looks at blood flow in a part of the fetal heart called the aortic isthmus in pregnancies where the baby is not growing well (fetal growth restriction). Researchers will compare Doppler measurements between affected fetuses and healthy ones to see if these patterns can help detect how severe the condition is. The goal is to improve monitoring and decision-making for these high-risk pregnancies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could improve early detection of fetal distress in growth-restricted pregnancies, potentially guiding timely interventions.
- What could go wrong
- This is an observational study with a small sample size, so findings may not apply broadly. It does not test a treatment, so direct patient benefit is not guaranteed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Singleton pregnant women attending the fetal medicine unit at Women's Health Hospital, Assiut University, including both fetal growth restriction cases and normal controls.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Singleton pregnancy * Diagnosis of fetal growth restriction (estimated fetal weight \<10th percentile for gestational age) * Written informed consent obtained from the patient Exclusion Criteria: * Major fetal structural anomalies, especially cardiovascular anomalies * Multiple pregnancy (e.g., twins) * Suspected chromosomal abnormalities or genetic syndromes * Severe maternal comorbidities affecting Doppler results (e.g., uncontrolled diabetes, lupus) * Uncertain gestational age * Fetal demise before Doppler assessment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a simple ultrasound spot hidden heart strain in Growth-Restricted pregnancies?
- Can fetal heart scans predict risk in growth restriction?
- Ultrasound may predict hidden placental problems before delivery
- Placental protein clues may unlock mystery of poor fetal growth
- New ultrasound technique could unlock secrets of placental health in pregnancy
- New screening method could spot pregnancy risks earlier