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Could a simple blood test predict severe preeclampsia?

NCT ID NCT07265336

Knowledge-focused Sponsor: Saint Thomas Hospital, Panama Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study looks at whether a blood gas measurement called base excess differs between pregnant women with severe preeclampsia and those with normal blood pressure. Researchers will test 100 women before delivery to see if abnormal base excess levels are linked to more severe disease. If confirmed, base excess could become a new tool to help predict complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify a simple blood test marker to predict the severity of preeclampsia, potentially guiding earlier interventions.
What could go wrong
This is an early observational study with only 100 participants, so results may not apply to all patients. The link between base excess and preeclampsia severity is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Aug 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Gestational age: 24-40 weeks * Cases: Diagnosis of severe preeclampsia * Control: Normal blood pressure Exclusion Criteria: * Metabolic conditions that could hinder the results (diabetic ketoacidosis, sepsis, renal failure). * Clinical conditions that could hinder the results (diarrhea, vomit) * Recent use of bicarbonate

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Conditions

The condition(s) this trial relates to.

preeclampsia severe pre-eclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Preeclampsia Severe preeclampsia

Contacts and locations

Locations

  • Saint Thomas Hospital

    Panama City, Provincia de Panamá, Panama

More trials for these conditions

Other studies related to the condition(s) this trial covers.