Olive compound could ease pregnancy hypertension
NCT ID NCT07298759
First seen Jun 25, 2026 · Last updated Aug 27, 2026 · Updated 3 times
Summary
This study tests whether hydroxytyrosol, a natural antioxidant from olives, can improve blood vessel function in pregnant women with high blood pressure. Fifty-two women will take either the supplement or a placebo for 4 weeks. Researchers will measure changes in blood markers and ultrasound scans of the uterine and arm arteries.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Hydroxytyrosol (a natural compound from olives)
- What this could lead to
- If it works, this could point toward a simple supplement to help manage blood pressure and blood vessel health during pregnancy.
- What could go wrong
- This is a small, early-phase trial with only 52 participants. The results may not be strong enough to change practice, and the supplement may not show clear benefits over placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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52 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Singleton pregnancy with a live intrauterine fetus 2. Gestational age 24-32 weeks. Gestational age is confirmed based on: * Last Menstrual Period (LMP) * First trimester ultrasound biometry 3. Belongs to the Hypertensive Disorders of Pregnancy group, with the following criteria: * Gestational hypertension and preeclampsia according to ACOG 2018 criteria * Chronic hypertension according to ACOG 2019 criteria * Superimposed preeclampsia according to ACOG 2018 criteria Exclusion Criteria: 1. Pregnancy with infection, including chronic infections such as tuberculosis (TB), HIV, or hepatitis B 2. Pregnancy with other complications (e.g., diabetes mellitus, heart disease, kidney disease, liver disease, malignancy, autoimmune disorders) 3. Refusal to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dr. Cipto Mangunkusumo National Central Public Hospital
Jakarta, Jakarta Special Capital Region, 10430, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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