Pill vs. shot: can glyburide replace insulin for gestational diabetes?
NCT ID NCT01731431
First seen Oct 31, 2025 · Last updated Jun 21, 2026 · Updated 31 times
Summary
This study tested whether the diabetes pill glyburide works as well as insulin shots for treating gestational diabetes in pregnant women. Over 900 women participated, and researchers looked at baby health issues like high birth weight, low blood sugar, and jaundice. The goal was to see if the pill could be a simpler alternative to daily injections.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Locations
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Marie-Victoire Senat
Paris, 94270, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Glyburide (a pill to lower blood sugar)
What this could lead to
If glyburide works as well as insulin, it could offer a simpler, pill-based option for managing gestational diabetes instead of daily injections.
What could go wrong
This is a completed Phase 3 trial, but non-inferiority means it aims to show glyburide is not worse than insulin, not necessarily better. Results may not apply to all women, and glyburide may have different side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.