New ultrasound technique could spot dangerous placenta condition earlier
NCT ID NCT02302573
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a special ultrasound using contrast dye can better diagnose placenta accreta, a condition where the placenta grows too deeply into the womb and can cause severe bleeding after birth. Researchers studied 80 pregnant women at high risk for this condition. The goal was to see if this imaging method is more accurate than current standard tests.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Start date
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May 2009
- Finished
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Aug 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pregnant patient having any of the following two conditions: * Scar uterus (previous cesarean) with placenta previa partly or wholly on the uterine scar * Placenta praevia and patient aged over 35 years * Term \> 34 weeks of amenorrhea * More than 18 years old * Inform consent form signed * affiliated to medical insurrance Exclusion Criteria: * Inability to understand information * Contraindications to the contrast medium Sonovue: * Hypersensitivity to hexafluorinated sulphur or any other components of Sonovue * Recent acute coronary syndrome (within 6 months before the intervention) * Unstable ischemic heart disease (myocardial infarction being formed or evolving, typical angina of rest in the previous month) * Significant worsening of cardiac symptoms between the pre anaesthesia consultation and intervention * Recent intervention (less than 6 months) on coronary arteries or other factor suggesting clinical instability (changes in ECG, changes in clinical or biological parameters) * Acute heart failure or heart failure stage III or IV * Severe arrhythmias * Right-left shunt * Acute endocarditis * Valve prothesis * Severe pulmonary hypertension (pulmonary artery pressure \> 90mmHg) * Systemic hypertension uncontrolled * Respiratory distress syndrome
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU La Millétrie
Poitiers, 86000, France
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University Hospital of Tours
Tours, 37044, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Womb healing after placenta accreta: a closer look
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- New study aims to predict dangerous placenta complications before delivery